中文名稱：肺癌腫瘤阻抑基因1抗體，SynCAM/TSLC1抗體

英文名稱：Anti-SynCAM/TSLC1

貨號：BYK-1147R

克隆類型：polyclonal or monoclonal

抗體來源：Rabbit or Mouse
性狀：Lyophilized or Liquid
產(chǎn)品類型：一抗
保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
標記物：可以提供抗體相對應的 HRP   Biotin  Gold   RBITC   AP   FITC   Cy3 Cy5   Cy5.5   Cy7   PE   PE-Cy3   PE-CY5   PE-CY5.5   PE-CY7   APC   Alexa Fluor 350    Alexa Fluor 488    Alexa Fluor 555     Alexa Fluor 647 等標記物抗體，詳情請詢！

肺癌腫瘤阻抑基因1抗體，SynCAM/TSLC1抗體 詳細介紹：

Mediates homophilic cell-cell adhesion in a Ca（2+）-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca（2+）-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer （NSCLC） cells. Interaction with CRTAM promotes natural killer （NK） cell cytotoxicity and interferon-gamma （IFN-gamma） secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. May act as a synaptic cell adhesion molecule that drives synapse assembly. May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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