目錄:北京索萊寶科技有限公司>>抗體>>Polyclonal Antibody>> K107479PAnti-RPS6 Polyclonal Antibody
供貨周期 | 現(xiàn)貨 | 規(guī)格 | 50ul/100ul |
---|---|---|---|
貨號 | K107479P | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)業(yè) |
主要用途 | WB IHC |
Anti-RPS6 Polyclonal Antibody
英文名稱 | Anti-RPS6 Polyclonal Antibody |
---|---|
宿主 | Rabbit |
別名 | S6;ribosomal protein S6 |
應(yīng)用 | WB IHC |
稀釋比例 | WB 1:5000-8000. IHC 1:50-200. |
交叉反應(yīng) | Human Mouse Rat |
蛋白分子量 | 29kDa |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
純化方法 | Affinity purification |
亞型 | IgG |
免疫原 | A synthetic peptide of human RPS6 |
Swiss Prot | P62753 |
Subcellular Locations | Cytosol Endoplasmic reticulum Nucleus |
克隆類型 | Polyclonal Antibody |
背景資料 | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. |
多克隆抗體
由于多克隆抗體通常包含抗某一抗原的不同表位的抗體,所以,在深固定的樣本中也會很好地發(fā)揮效應(yīng),在石蠟包埋組織切片的染色中,多克隆抗體常選用。根據(jù)實驗的不同需要,多克隆抗體應(yīng)用于相應(yīng)抗原的標(biāo)記。此外,在農(nóng)業(yè)生產(chǎn)中,多克隆抗體被用于農(nóng)藥殘留現(xiàn)場監(jiān)測;在臨床應(yīng)用中,多克隆抗體主要用于病原物的檢測、疾病的診斷及治療,如作為蛋白類免疫抑制劑用于移植反應(yīng)和自身免疫病的治療。
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