目錄:北京索萊寶科技有限公司>>抗體>>Polyclonal Antibody>> K000405PAnti-PABPC4 Polyclonal Antibody
供貨周期 | 現(xiàn)貨 | 規(guī)格 | 50ul/100ul |
---|---|---|---|
貨號 | K000405P | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)業(yè) |
主要用途 | WB IHC IF |
Anti-PABPC4 Polyclonal Antibody
英文名稱 | Anti-PABPC4 Polyclonal Antibody |
---|---|
宿主 | Rabbit |
別名 | APP-1;APP1;PABP4;iPABP |
應(yīng)用 | WB IHC IF |
稀釋比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
交叉反應(yīng) | Human Mouse Rat |
蛋白分子量 | 71kDa |
Gene ID | 8761 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
儲存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
純化方法 | Affinity purification |
亞型 | IgG |
免疫原 | A synthetic peptide of human PABPC4 |
性狀 | 液體 |
Public Immunogen Range | A synthetic peptide of human PABPC4 |
Subcellular Locations | Cytoplasm |
Swiss Prot | Q13310 |
克隆類型 | Polyclonal Antibody |
背景資料 | Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
多克隆抗體
由于多克隆抗體通常包含抗某一抗原的不同表位的抗體,所以,在深固定的樣本中也會很好地發(fā)揮效應(yīng),在石蠟包埋組織切片的染色中,多克隆抗體常選用。根據(jù)實(shí)驗(yàn)的不同需要,多克隆抗體應(yīng)用于相應(yīng)抗原的標(biāo)記。此外,在農(nóng)業(yè)生產(chǎn)中,多克隆抗體被用于農(nóng)藥殘留現(xiàn)場監(jiān)測;在臨床應(yīng)用中,多克隆抗體主要用于病原物的檢測、疾病的診斷及治療,如作為蛋白類免疫抑制劑用于移植反應(yīng)和自身免疫病的治療。
索萊寶公司創(chuàng)立于2004年是一家擁有大批專業(yè)研發(fā)人員,專注于生物產(chǎn)品不斷完善和創(chuàng)新的公司。我們產(chǎn)品覆蓋面廣,品質(zhì)可靠。在優(yōu)化試劑產(chǎn)品線的同時(shí),經(jīng)過多年研發(fā)經(jīng)驗(yàn)的積累,也推出了新的抗體產(chǎn)品線。初期,大批科研人員精心設(shè)計(jì),齊力設(shè)計(jì)出好的抗體產(chǎn)品;后期,質(zhì)檢工作者嚴(yán)格的質(zhì)量把控為我們保駕護(hù)航。終,在我們的共同努力之下,帶您見證索萊寶公司的又一奇跡。
運(yùn)輸說明:
極低溫產(chǎn)品:極低溫產(chǎn)品運(yùn)輸過程中加裝干冰運(yùn)輸。用干冰把產(chǎn)品包裹起來,再用泡沫盒密封,膠帶層層粘住泡沫盒,放入索萊寶的箱子,然后交付給合作快遞,安全快速高效放心的送客戶的手中,保證產(chǎn)品的性質(zhì)穩(wěn)定如一,為您的實(shí)驗(yàn)保駕護(hù)航。
低溫產(chǎn)品:低溫產(chǎn)品運(yùn)輸過程中加裝索萊寶冰袋運(yùn)輸。事先用冰袋把產(chǎn)品包裹起來,再使用泡沫盒密封,用膠帶嚴(yán)實(shí)密封泡沫盒,再放入索萊寶的箱子(保溫效果少可以持續(xù)一周),然后交付給合作快遞,安全快速高效放心的送客戶的手中,保證產(chǎn)品的性質(zhì)穩(wěn)定如一,為您的實(shí)驗(yàn)保駕護(hù)航。
常溫產(chǎn)品:常溫產(chǎn)品運(yùn)輸過程中無需加冰或者特殊包裝。產(chǎn)品由公司庫房人員快速配貨,準(zhǔn)確快速高效的快遞保證產(chǎn)品快速送達(dá)您的手中。
(空格分隔,最多3個(gè),單個(gè)標(biāo)簽最多10個(gè)字符)