美國Primary Rat Podocyte大鼠原代腎足細(xì)胞
美國PrimCells原代細(xì)胞：PrimCells的原代細(xì)胞產(chǎn)品采用*的高效提取方法， 分離，并通過盡量縮短體外培養(yǎng)時間從而保證其更接近體原始狀態(tài)，以適應(yīng)客戶對細(xì)胞品質(zhì)的嚴(yán)格要求。PrimCells亦是多種腎臟來源原代細(xì)胞的世界*供應(yīng)商，為多家藥物研發(fā)企業(yè)提供藥物藥效與毒理測試。此外，PrimCells還開發(fā)出多種轉(zhuǎn)基因胚胎干細(xì)胞、原代胚胎成纖維細(xì)胞等產(chǎn)品，是干細(xì)胞與重編程領(lǐng)域的報告基因原代細(xì)胞提供商。
| Species: | Sprague Dawley | Catalog Number: | PCKDR01 |
| Cell Number: | ~1x106 | Storage/Shipping: | Freshly Isolated |
Introduction:
Podocytes are a group of terminally differentiated cells located in the outer aspect of glomerular basement membrane (GBM). They have special morphology with multiple long foot processes that cover the entire outer surface of the capillary of glomerulus and form a tight barrier to filter the blood and form the initial urine1. These cells are very important to maintain the normal function of the kidney and podocyte injury could result in massive proteinuria and eventually kidney failure2, 3.
PrimCells is proud to isolate and provide the primary cultures of podocytes from Sprague Dawley rats to the research community. These cells have been isolated using traditional sieving method and are confirmed to express typical podocyte markers such as Nephrin, Synaptopodin and WT1 and can be a valuable tool to study the function of genes in nephrology and/or drug induced toxicity in glomerular injury.
美國PrimCells品牌介紹
PrimCells是位于美國加州圣迭戈的一家專業(yè)致力于細(xì)胞產(chǎn)品研發(fā)和解決方案提供的業(yè)內(nèi)技術(shù)。
公司匯集了*的生物醫(yī)藥技術(shù)專家，獨立開發(fā)了多項原代細(xì)胞和干細(xì)胞相關(guān)的專有技術(shù)。 公司以“細(xì)胞研究的*選擇”為宗旨，自主研發(fā)超過70種創(chuàng)新產(chǎn)品，*多個特種細(xì)胞市場的空白。例如其誘導(dǎo)性表達(dá)細(xì)胞庫和高效3D皮膚培養(yǎng)系統(tǒng)，皆為該類產(chǎn)品目前市場上少數(shù)的規(guī)?；?yīng)商。此外，公司以高質(zhì)量的數(shù)據(jù)與快速穩(wěn)定的項目完成時間，長期為多家制藥公司提供解決方案，獲得用戶廣泛贊譽。
PrimCells產(chǎn)品線：
- 報告基因干細(xì)胞 2. 原代細(xì)胞（含報告基因原代細(xì)胞） 3. 誘導(dǎo)性穩(wěn)定細(xì)胞株
4. 人源重組蛋白 5. 創(chuàng)新型培養(yǎng)試劑
PrimCells 解決方案
1.誘導(dǎo)性穩(wěn)定細(xì)胞株開發(fā) 2. 原代細(xì)胞開發(fā) 3. 藥物體外毒理和效能測試 4. 3D-皮膚培養(yǎng)
PrimCells合作伙伴及客戶:
A．生物制藥公司：輝瑞(Pfizer), 諾華(Novartis), 禮來(Eli2 Lilly),. Amgen, EMD Millipore, Regeneron等公司的毒理和醫(yī)藥研發(fā)部門
B．科研機構(gòu)：冷泉港實驗室，哈佛醫(yī)學(xué)院, 麻省理工（MIT）,， UCSF, NYU, Salk, UIUC, USC等
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