A large percentage of pharmaceutical products are formulated as solids due to their ease of manufacture and packaging, and for the convenience of the patient. However, pharmaceutical compounds can often exist in more than one solid state form, including polymorphs and hydrates (pseudo-polymorphs). Since the solid state structure has potentially significant impact on the stability and bioavailability of the final product, it is essential that the solid state energetics of the compound be characterized and understood.
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