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南京科佰生物科技有限公司
主營(yíng)產(chǎn)品： atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫購(gòu)買 |
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聯(lián)系電話
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南京科佰生物科技有限公司
主營(yíng)產(chǎn)品： atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫購(gòu)買 |
聯(lián)系電話
| 參考價(jià) | 面議 |
更新時(shí)間：2022-05-06 09:21:07瀏覽次數(shù)：577
聯(lián)系我們時(shí)請(qǐng)說明是化工儀器網(wǎng)上看到的信息，謝謝!
| 供貨周期 | 現(xiàn)貨 | 規(guī)格 | T-25 Flask |
|---|---|---|---|
| 貨號(hào) | CBP73253 | 應(yīng)用領(lǐng)域 | 生物產(chǎn)業(yè) |
| 主要用途 | 僅限科研使用 |
CBP73253 | |
| I. Introduction | |
Cell Line Name： | CSF3R T618I/BaF3 |
Host Cell: | Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
| II.Background | |
CSF3R T618I lies within the extracellular domain proximal to the transmembrane domain of the Csf3r protein (PMID: 23656643). T618I confers a gain of function to the Csf3r protein as demonstrated by increased proliferation and increased downstream Jak-Stat signaling in transformed cells in culture (PMID: 23656643). | |
| III. Representative Data | |
1.WB of CSF3R T618I/BaF3
| |
2. Anti-proliferation assay | |
| |
Figure 2. Anti-proliferation assay of three reference compounds on the CSF3R T618I/BaF3. | |
