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南京科佰生物科技有限公司
主營產(chǎn)品： atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫購買 |
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南京科佰生物科技有限公司
主營產(chǎn)品： atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫購買 |
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更新時(shí)間：2022-09-14 09:23:47瀏覽次數(shù)：463
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| 供貨周期 | 現(xiàn)貨 | 規(guī)格 | 1ug |
|---|---|---|---|
| 貨號(hào) | CBP10522 | 應(yīng)用領(lǐng)域 | 生物產(chǎn)業(yè) |
CBP10522 | |
| Format | Genomic DNA |
| Description | NRAS G12R is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). G12R has not been characterized, but can be predicted to confer a loss of function on Nras protein based on the effects of HRAS G12R and NRAS G12R, which results in decreased GTPase activity, activation of downstream pathways, and transformation of cultured cells (PMID: 6092966, PMID: 26037647, PMID: 23455880). |
| Technical Data | |
| DNA Change: | c.34G>C |
| AA Change | p.G12R |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | NM_002524.5 |
| Cosmic ID | COSM561 |
| Chr position(GRCh37) | chr1:115258748 |
| Buffer: | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purity | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
