 |
南京科佰生物科技有限公司
主營產(chǎn)品： atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫購買 |
11
聯(lián)系電話
|
南京科佰生物科技有限公司
主營產(chǎn)品： atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫購買 |
聯(lián)系電話
| 參考價 | 面議 |
更新時間：2023-10-24 15:03:55瀏覽次數(shù)：666
聯(lián)系我們時請說明是化工儀器網(wǎng)上看到的信息，謝謝!
| 供貨周期 | 現(xiàn)貨 | 規(guī)格 | 1ug |
|---|---|---|---|
| 貨號 | CBP10270 | 應(yīng)用領(lǐng)域 | 生物產(chǎn)業(yè) |
CBP10270 | |
| Format | Genomic DNA |
| Description | ERBB2 (HER2) L755S lies within the protein kinase domain of the Erbb2 (Her2) protein (UniProt.org). L755S results in increased phosphorylation of Erbb2 (Her2), activation of downstream signaling, is transforming in cell culture (PMID: 29967253), and is associated with resistance to Erbb2 (Her2)-targeted therapies (PMID: 22046346, PMID: 28487443). |
| Technical Data | |
| DNA Change | c.2264T>C |
| AA Change | p.L755S |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50% |
| Transcript | ENST00000269571 |
| Cosmic ID | N/A |
| Chr position(GRCh37) | chr17:37880220 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
