英文名稱 CLEC2D
中文名稱 CLEC2D蛋白抗體
別    名 C-type lectin domain family 2 member D; C type lectin domain family 2 member D isoform 5; CLAX; LLT1; OCIL; Lectin like NK cell receptor; Lectin like transcript 1; Osteoclast inhibitory lectin; CLC2D_HUMAN; CLEC2D; CLEC2D protein; Lectin-like NK cell receptor; Lectin-like transcript 1; LLT-1; Osteoclast inhibitory lectin.
 CLEC2D蛋白抗體   
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 免疫學(xué)  細(xì)胞表面分子  t-淋巴細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 10kDa
細(xì)胞定位 細(xì)胞膜 細(xì)胞外基質(zhì) 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CLEC2D
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
 產(chǎn)品介紹 background:
This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified, but the full-length nature of every transcript has not been defined.

Function:
Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans.

Subunit:
Homodimer or heterodimer; disulfide-linked.

Subcellular Location:
Cell membrane; Single-pass type II membrane protein. Cell surface.
Isoform 2, 4: Endoplasmic reticulum.

Tissue Specificity:
Detected in fetal heart, brain, lung, chondrocytes, perichondrium and osteoblasts, and in adult splenocytes, thymocytes, lymph-node cells, osteoblasts, growth plate chondrocytes and skeltal muscle overlying the bone (at protein level). Ubiquitous. Detected in thymus, bone marrow, lung, gut, heart, skeletal muscle, ovary, spleen, ileum, liver and kidney.

Similarity:
Contains 1 C-type lectin domain.

Gene ID:
29121

Database links:

Entrez Gene: 29121 Human

Entrez Gene: 93694 Mouse

Entrez Gene: 113937 Rat

Omim: 605659 Human

SwissProt: Q9UHP7 Human

SwissProt: Q91V08 Mouse

SwissProt: Q925N7 Rat

Unigene: 268326 Human

Unigene: 197536 Mouse

Unigene: 22573 Rat

Important Note:
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