Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) 抗體

抗原
Autophagy/beclin-1 Regulator 1 (AMBRA1)
別名 2310079H06Rik, A130023A14, AA474864, AV021921, D030051N19Rik, mKIAA1736, Nyw1, DCAF3, WDR94
抗原表位
其他選擇 N-Term
N-Term(22),C-Term (14),AA 1-50 (2),AA 27-55 (2),AA 1200-1250 (1),AA 14-239 (1),AA 807-1092 (1),Internal Region (1)
適用
其他選擇 Human, Murine
Human(59),Murine (47),Rat ((Rattus)) (31),Chicken (13),Dog (Canine) (12),Bovine (1)
宿主
其他選擇 Rabbit
Rabbit(66),Mouse (1)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
Alexa Fluor 350(1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Biotin (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),FITC (1),HRP (1)
應(yīng)用范圍
其他選擇 ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Western Blotting (WB)(56),Immunohistochemistry (IHC) (29),ELISA (27),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (14),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunoprecipitation (IP) (7),Enzyme Immunoassay (EIA) (4),Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (4),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (3),Immunoassay (IA) (1),Immunofluorescence (IF) (1),Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
規(guī)格 0.1 mg
發(fā)貨至 中國(guó) (更改)
發(fā)貨時(shí)間 24至29個(gè)工作日

Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) 抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

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免疫原 The immunogen for anti-Ambra1 antibody: antibody was raised against a 18 amino acid peptide from near the amino terminus of human Ambra1.
預(yù)測(cè)反應(yīng) Human Mouse
產(chǎn)品特性 Autophagy, The Process Of Bulk Degradation Of Cellular Proteins Through An Autophagosomic-Lysosomal Pathway Is Important For Normal Growth Control And May Be Defective In Tumor Cells. It Is Involved In The Preservation Of Cellular Nutrients Under Starvation Conditions As Well As The Normal Turnover Of Cytosolic Components. Beclin-1, A Principal Regulator Of Autophagosome Formation, Is In Turn Regulated By Ambra1. Ambra1 Associates With Beclin-1 Through A Region Near Its Center As Determined By Yeast Two-Hybrid Assay. Null Mutations In This Gene In Mice Resulted In Embryonic Lethality With Severe Neural Tube Defects Associated With Autophagy Impairment, Accumulation Of Ubiquitinated Proteins, Unbalanced Cell Proliferation And Excessive Apoptotic Death . Furthermore, Down-Regulation Of Ambra1 In Cultured Cells Though Rna Interference Decreased The Level Of Rapamycin- And Nutrient Starvation-Induced Autophagy. Multiple Isoforms Of Ambra1 Are Known To Exist.
純化方法 Affinity chromatography purified via peptide column

Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) 抗體目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 Ambra1
背景 (NT) Autophagy Regulating Protein

使用細(xì)節(jié)

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Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) 抗體使用細(xì)節(jié)

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應(yīng)用備注 Ambra1 antibody can be used for the detection of Ambra1 by Western blot at 2 - 4?μg/mL
限制 For Research Use only

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注意事項(xiàng) As with all antibodies care should be taken to avoid repeated freeze thaw cycles.
Antibodies should not be exposed to prolonged high temperatures.
儲(chǔ)存條件 4 °C
儲(chǔ)存方法 Ambra1 antibody can be stored at 4 °C
有效期 12 months

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