DOK1抗體

抗原
Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1)
別名 4432404K01Rik, ARTC4, DO, DOK1, AW557123, p62DOK, Dok-1, P62DOK
抗原表位
其他選擇 C-Term
pTyr398(40),pTyr362 (39),N-Term (15),C-Term (13),pSer450 (13),Tyr362 (6),Tyr398 (6),AA 360-364 (5),AA 1-481 (4),AA 396-400 (3),AA 24-39 (2),AA 425-439 (2),AA 9-39 (2),AA 277-481 (1),AA 329-378 (1),AA 365-414 (1),AA 9-277 (1),Arg392 (1),Pro356 (1)
適用
其他選擇 Human
Human(210),Murine (120),Rat ((Rattus)) (120),Bovine (36),Dog (Canine) (36),Pig (Porcine) (36)
宿主
其他選擇 Rabbit
Rabbit(209),Mouse (2)
克隆類型
多克隆
標記
其他選擇 非結(jié)合性
Biotin(6),FITC (6),HRP (6),Alexa Fluor 350 (4),Alexa Fluor 488 (4),Alexa Fluor 555 (4),Alexa Fluor 647 (4),Cy3 (4),Cy5 (4),Cy5.5 (4),Cy7 (4),APC (1),Alkaline Phosphatase (AP) (1),PE (1)
應(yīng)用范圍
其他選擇 Western Blotting (WB)
Western Blotting (WB)(165),Immunohistochemistry (IHC) (73),ELISA (53),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (45),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (40),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (15),Immunofluorescence (IF) (14),Flow Cytometry (FACS) (10),Immunocytochemistry (ICC) (10),Immunoassay (IA) (4),Immunoprecipitation (IP) (2),Enzyme Immunoassay (EIA) (1),Immunohistochemistry (Acetone-fixed) (IHC (af)) (1),Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
[Pubmed] 2 references available
規(guī)格 50 μg
發(fā)貨至 中國 (更改)
發(fā)貨時間 9至12個工作日

DOK1抗體

產(chǎn)品細節(jié)

引用 圖像 貯存及處理 使用細節(jié) 目標詳細情況 回頁首

產(chǎn)品細節(jié)

顯示 隱藏
免疫原 Synthetic peptide directed towards the C terminal of human DOK1
序列 EPGTATGSGI KSHNSALYSQ VQKSGASGSW DCGLSRVGTD KTGVKSEGST
預測反應(yīng) Human : 100 %, Horse : 80 %
產(chǎn)品特性 This is a rabbit polyclonal antibody against DOK1. It was validated on Western Blot using a cell lysate as a positive control.
純化方法 Affinity Purified

目標詳細情況

引用 圖像 貯存及處理 使用細節(jié) 回頁首

目標詳細情況

顯示 隱藏
別名 DOK1
背景 DOK1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
分子量 53 kDa
基因ID 1796
NCBI Accession NM_001381, NP_001372
UniProt Q99704
研究領(lǐng)域 Cancer, Tyrosine Kinases

使用細節(jié)

引用 圖像 貯存及處理 目標詳細情況 回頁首

使用細節(jié)

顯示 隱藏
應(yīng)用備注 Optimal working dilutions should be determined experimentally by the investigator.
說明

Antigen size: 481 AA

限制 For Research Use only

貯存及處理

引用 圖像 使用細節(jié) 目標詳細情況 回頁首

貯存及處理

顯示 隱藏
狀態(tài) Lyophilized
溶解方式 Add 50 µL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項 Avoid repeated freeze-thaw cycles.
儲存條件 -20 °C
儲存方法 For longer periods of storage, store at -20 °C

xy-4866R Nephrin腎小球細胞粘附分子受體抗體
xy-11095R NEGR1神經(jīng)生長調(diào)節(jié)蛋白1抗體
xy-11103R Netrin G1/G2軸突生長誘向因子G2抗體
xy-11192R NG2黑色素瘤硫酸軟骨素蛋白多糖4抗體
xy-9891R NDST1NDST1蛋白抗體
xy-11299R NAB2EGR1結(jié)合蛋白2抗體
xy-9587R Alpha-synuclein (nitro-Tyr39)硝基化α-突觸核蛋白
xy-11302R Nkx2.2NK2轉(zhuǎn)錄樣蛋白B抗體
xy-4893R NPTX1神經(jīng)細胞正五聚體1抗體
xy-7843R NUP160核孔蛋白NUP160抗體
xy-7841R NUDC細胞核分離基因C蛋白抗體
xy-7842R phospho-NUDC(Ser326)磷酸化細胞核分離基因C蛋白抗體
xy-11573R Neuro D神經(jīng)特異性轉(zhuǎn)錄因子DPF1抗體
xy-11591R NAT8 + NAT8BN-乙酰轉(zhuǎn)移酶8抗體
xy-11592R NAT8BN-乙酰轉(zhuǎn)移酶8B抗體
xy-11595R NOMO1NOMO蛋白抗體
xy-6945R NKCC1鈉鉀離子轉(zhuǎn)運蛋白1抗體
xy-8601R hydrogen exchanger 3鈉離子/氫離子交換蛋白3抗體
xy-9582R phospho-NHE3(Ser552)磷酸化鈉離子/氫離子交換蛋白3抗體
xy-11017R NPTX2神經(jīng)細胞穿透素2抗體
xy-11102R Neprilysin 2腦啡肽酶2抗體
xy-4976R H1N1 NucleoproteinA型流感病毒核蛋白抗體
xy-11094R NCAM2神經(jīng)細胞粘附分子2抗體
xy-6911R Nidogen巢蛋白1抗體
xy-8150R NPFF嗎啡痛覺調(diào)節(jié)肽NPFF抗體
xy-6631R Neurotensin神經(jīng)緊張素抗體
xy-6632R NESG1鼻咽上皮細胞特異性蛋白1抗體
xy-5782R NR2F2載脂蛋白AI調(diào)節(jié)蛋白1抗體
xy-5829R NG2黑色素瘤硫酸軟骨素蛋白多糖抗體
xy-5755R Nucleoprotein TPR核蛋白易位啟動子區(qū)域TPR抗體
xy-11900R NFIX核因子1X抗體
xy-6389R NIRF 環(huán)指蛋白107抗體