ICAM1 抗體

抗原
Intercellular Adhesion Molecule 1 (ICAM1)
別名 BB2, CD54, P3.58, Icam-1, Ly-47, MALA-2, ICAM, ICAM-1, ICAM1
抗原表位
其他選擇 AA 1-493
pTyr512(38),AA 1-480 (16),C-Term (13),AA 1-485 (10),AA 1-493 (9),AA 28-480 (7),N-Term (6),AA 1-532 (5),Tyr512 (4),AA 301-532 (3),AA 510-514 (3),Middle Region (3),AA 253-267 (2),AA 28-483 (2),AA 41-464 (2),AA 46-301 (2),AA 1-371 (1),AA 1-50 (1),AA 1-533 (1),AA 198-537 (1),AA 214-532 (1),AA 26-480 (1),AA 328-465 (1),AA 339-523 (1),AA 457-506 (1),AA 467-517 (1),AA 479-528 (1),AA 488-514 (1),Domain D1 (1),Gln506 (1),Internal Region (1),Ser518 (1)
適用
其他選擇 Rat ((Rattus))
Human(467),Murine (121),Rat ((Rattus)) (68),Bovine (8),Dog (Canine) (2),Monkey (1)
宿主
其他選擇 Rabbit
Mouse(306),Rabbit (214),Rat (68),Sheep (6),Hamster (4),Goat (3)
克隆類型 (克隆位點(diǎn))
單克隆 (37)
標(biāo)記
其他選擇 FITC
Biotin(56),FITC (52),PE (50),APC (9),Alexa Fluor 488 (7),Alexa Fluor 647 (7),HRP (6),Alexa Fluor 350 (5),Alexa Fluor 555 (5),Cy3 (5),Cy5 (5),Cy5.5 (5),Cy7 (5),PerCP (3),Alexa Fluor 546 (2),DyLight 488 (1),DyLight 550 (1),DyLight 594 (1),DyLight 650 (1),DyLight 755 (1),Magnetic Particles (1),Sepharose (1)
應(yīng)用范圍
其他選擇 Flow Cytometry (FACS)
Flow Cytometry (FACS)(331),Western Blotting (WB) (231),ELISA (136),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (107),Immunoprecipitation (IP) (99),Immunohistochemistry (Frozen Sections) (IHC (fro)) (96),Immunohistochemistry (IHC) (64),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (50),Immunofluorescence (IF) (38),Immunocytochemistry (ICC) (36),Functional Studies (Func) (29),Blocking Reagent (BR) (16),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (16),Enzyme Immunoassay (EIA) (12),Immunoassay (IA) (6),Immunohistochemistry (Fixed) (IHC (fx)) (5),Dot Blot (DB) (4),Blocking Antibody (Inhibition) (3),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3),ELISA (Capture) (2),ELISA (Detection) (2),Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (1),Intracellular Staining (ICS) (1),Proximity Ligation Assay (PLA) (1)
規(guī)格 50 tests
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ICAM1 抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

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免疫原 Recombinant Rat ICAM-1 / CD54 protein
克隆位點(diǎn) 37
亞型 IgG
特異性 Rat ICAM-1 / CD54
產(chǎn)品特性 This antibody was obtained from a rabbit immunized with purified, recombinant Rat ICAM-1 / CD54 (rR ICAM-1 / CD54, Q00238-1, Met1-Thr493) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.

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目標(biāo)詳細(xì)情況

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別名 ICAM1
背景 ICAM1 (Inter-Cellular Adhesion Molecule 1), also known as CD54, is a type of intercellular adhesion molecule constituy present in low concentrations in the membranes of leukocytes and endothelial cells. As an endothelial and leukocyte-associated transmembrane protein, ICAM1 is well known for its importance in stabilizing cell-cell interactions and facilitating leukocyte endothelial transmigration.ICAM1 is a ligand for LFA-1 (integrin). When activated, leukocytes bind to endothelial cells via ICAM-1/LFA-1 interaction and then transmigrate into tissues. Presence with heavy glycosylation and other structural characteristics, ICAM1 possesses binding sites for a number of immune-associated ligands and serves as the binding site for entry of the major group of human Rhinovirus (HRV) into various cell types. ICAM1 also becomes known for its affinity for Plasmodium falciparum- infected erythrocytes (PFIE), providing more of a role in infectious disease.
UniProt Q00238-1

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使用細(xì)節(jié)

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應(yīng)用備注 Concentration: 2 μl/Test, 0.1 mg/ml
限制 For Research Use only

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貯存及處理

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狀態(tài) Liquid
緩沖液 Aqueous solution containing 0.5% BSA and 0.09% sodium azide
儲(chǔ)存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事項(xiàng) Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal
儲(chǔ)存條件 4 °C/-20 °C/-80 °C
儲(chǔ)存方法 This antibody is stable for 12 months from date of receipt when stored at 2 °C - 8 °C.
有效期 12 months

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