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CCL17抗體

參   考   價(jià): 1800

訂  貨  量: ≥1 

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更新時(shí)間:2015-01-04 10:08:10瀏覽次數(shù):401次

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CCL17抗體的概念:
Z初有人用電泳證明血清中抗體活性在γ球蛋白部分,故曾把抗體統(tǒng)稱(chēng)為丙種(γ)球蛋白。后來(lái)發(fā)現(xiàn),抗體并不都在γ區(qū);并且位于γ區(qū)的球蛋白,也不一定都具有抗體活性,規(guī)格:0.1ml/100?g、0.2ml/200?g

CCL17抗體

抗原
Chemokine (C-C Motif) Ligand 17 (CCL17)
別名 CCL17, A-152E5.3, ABCD-2, SCYA17, TARC, Abcd-2, Scya17, Scya17l, Tarc
抗原表位
其他選擇 AA 1-94
C-Term(12),AA 65-94 (7),AA 24-94 (5),AA 1-94 (3),AA 12-83 (1),AA 24-93 (1),AA 27-93 (1),AA 27-94 (1),AA 30-94 (1)
適用
其他選擇 Human
Human(61),Murine (22),Rat ((Rattus)) (21)
宿主
其他選擇 Mouse
Rabbit(63),Mouse (6),Rat (1)
克隆類(lèi)型 (克隆位點(diǎn))
單克隆 (5C8C9)
標(biāo)記
其他選擇 非結(jié)合性
Biotin(15),FITC (2),HRP (2),APC (1),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),PE (1)
zui低檢測(cè)濃度 0.3125 ng/well
應(yīng)用范圍
其他選擇 ELISA
Western Blotting (WB)(55),ELISA (45),Immunohistochemistry (IHC) (12),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (10),Immunocytochemistry (ICC) (7),Immunohistochemistry (Frozen Sections) (IHC (fro)) (7),Neutralization (Neut) (5),Enzyme Immunoassay (EIA) (4),Functional Studies (Func) (3),Immunofluorescence (IF) (2),Blocking Antibody (Inhibition) (1)
[Pubmed] 1 reference available
規(guī)格 50 μg
發(fā)貨至 中國(guó) (更改)

CCL17抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
克隆位點(diǎn) 5C8C9
亞型 IgG1
特異性 Human CCL17 / TARC
交叉反應(yīng) (詳細(xì)) No cross-reactivity in WB and ELISA with Insect cell lysate
產(chǎn)品特性 This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CCL17 / TARC (rh CCL17 / TARC, Q92583-1, Met 1-Ser 94). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
過(guò)濾 0.2 μm filtered

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 CCL17
背景 Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokin ligand 17 (CCL17), also known as thymus and activation regulated chemokine(TARC), is a small cytokine belonging to the C-C chemokine family. CCL17 is expressed maily in thymus and transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. CCL17 can induce chemotaxis in T cells by binding with the chemokine receptor CCR4.
UniProt Q92583-1

使用細(xì)節(jié)

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使用細(xì)節(jié)

顯示 隱藏
應(yīng)用備注 ELISA ELISA: 0.5-1 μg/mL This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human CCL17. The detection limit for Human CCL17 is approximay 0.3125 ng/well.
限制 For Research Use only

貯存及處理

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貯存及處理

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緩沖液 PBS with 5% trehalose
儲(chǔ)存液 Without preservative
注意事項(xiàng) Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
儲(chǔ)存條件 4 °C/-20 °C/-80 °C
儲(chǔ)存方法 This antibody can be stored at 2 °C-8 °C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 °C to -70 °C.
有效期 12 months

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