SERPIND1 抗體

抗原
serpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 1 (SERPIND1)
別名 HCII, AA985900, AI303446, Hcf2, D22S673, HC2, HCF2, HLS2, LS2, THPH10, rls2var1
抗原表位
其他選擇 AA 1-499
AA 1-499(13),AA 1-478 (6),Internal Region (2),N-Term (2),AA 20-499 (1),AA 25-235 (1),AA 276-499 (1),AA 38-317 (1),AA 41-90 (1),Asp68 (1),Middle Region (1)
適用
其他選擇 Human
Human(49),Murine (14),Rat ((Rattus)) (9)
宿主
其他選擇 Mouse
Rabbit(35),Goat (10),Mouse (8),Sheep (3)
克隆類型 (克隆位點)
單克隆 (7)
標記
其他選擇 非結(jié)合性
HRP(2),Biotin (1)
應用范圍
其他選擇 Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
ELISA(34),Western Blotting (WB) (22),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (12),Immunohistochemistry (IHC) (10),Immunofluorescence (IF) (9),Immunocytochemistry (ICC) (5),Immunoassay (IA) (4),Immunohistochemistry (Frozen Sections) (IHC (fro)) (3),Immunodiffusion (ID) (2),Immunoelectrophoresis (IEP) (2),Immunoprecipitation (IP) (2),Flow Cytometry (FACS) (1),Radial Immunodiffusion (RID) (1)
規(guī)格 50 μg
發(fā)貨至 中國 (更改)

SERPIND1 抗體

產(chǎn)品細節(jié)

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產(chǎn)品細節(jié)

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免疫原 Recombinant Human SerpinD1 protein
克隆位點 7
亞型 IgG1
特異性 Human SerpinD1
交叉反應 （詳細） No cross-reactivity in ELISA with Human SerpinC1 Human SerpinI1 Mouse SerpinD1 Mouse SerpinF1 Mouse SerpinF2
產(chǎn)品特性 This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SerpinD1 (rh SerpinD1, NP_000176.2, Met1-Ser499). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
純化方法 Affinity Purified
過濾 0.2 μm filtered

目標詳細情況

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目標詳細情況

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別名 SERPIND1
背景 SerpinD1, also known as heparin cofactor II (HCII), is a member of Serpin superfamily of the serine proteinase inhibitors. Mouse HCII is a glycoprotein expressed predominantly in liver that inhibits thrombin, and the rate of inhibition of thrombin is rapidly increased by Dermatan sulfate (DS), heparin (H) and glycosaminoglycans (GAG). The stimulatory effect of glycosaminoglycans on the inhibition is mediated, in part, by the N-terminal acidic domain of HCII. SerpinD1 also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner. It has been suggested that HCII plays an unique and important role in vascular homeostasis, and accordingly mutations in this gene or congenital HCII deficiency is potentially associated with thrombosis.
NCBI Accession NP_000176.2

使用細節(jié)

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使用細節(jié)

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應用備注 Immunochemistry - IHC-P: 5-20 μg/mL
限制 For Research Use only

貯存及處理

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貯存及處理

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緩沖液 PBS with 5% trehalose
儲存液 Without preservative
注意事項 Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
儲存條件 4 °C/-20 °C/-80 °C
儲存方法 This antibody can be stored at 2 °C-8 °C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 °C to -70 °C.
有效期 12 months

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