FSTL1抗體

抗原
Follistatin-Like 1 (FSTL1)
別名 fstl1, wu:fc75h02, zgc:110703, FSTL1, DKFZp469P101, FRP, FSL1, MIR198, AI316791, AW107808, Fstl, TSC-36, FLIK, Frp
抗原表位
其他選擇 AA 1-308
C-Term(16),AA 285-318 (8),N-Term (8),AA 1-308 (4),AA 20-306 (2),AA 20-308 (2),AA 280-308 (2),AA 1-209 (1),AA 19-306 (1),AA 246-308 (1),AA 46-293 (1)
適用
其他選擇 Human
Human(52),Rat ((Rattus)) (18),Murine (15),Bovine (13),Chicken (12),Dog (Canine) (12),Rhesus Monkey (3)
宿主
其他選擇 Rabbit
Rabbit(50),Goat (5),Mouse (2),Rat (2),Chicken (1)
克隆類型
多克隆
標記
其他選擇 非結合性
Biotin(5),FITC (2),HRP (2),APC (1),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),PE (1)
zui低檢測濃度 0.039 ng/well
應用范圍
其他選擇 ELISA
Western Blotting (WB)(48),ELISA (31),Immunohistochemistry (IHC) (21),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (13),Flow Cytometry (FACS) (10),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunocytochemistry (ICC) (5),Immunohistochemistry (Frozen Sections) (IHC (fro)) (5),Enzyme Immunoassay (EIA) (2),Immunofluorescence (IF) (1),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (1)
[Pubmed] 1 reference available
規(guī)格 100 μg
發(fā)貨至 中國 (更改)

FSTL1抗體

產(chǎn)品細節(jié)

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產(chǎn)品細節(jié)

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亞型 IgG
特異性 Human FSTL1 / FRP
產(chǎn)品特性 Produced in rabbits immunized with purified, recombinant Human FSTL1 / FRP (rh FSTL1, NP_009016.1, Met 1-Ile 308). Total IgG was purified by Protein A affinity chromatography.
純化方法 Affinity Purified
過濾 0.2 μm filtered

目標詳細情況

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目標詳細情況

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別名 FSTL1
背景 Follistatin-related protein 1 (FSTL1), is an extracellular glycoprotein whose functional significance in physiological and pathological processes is incompley understood. Recently, we have shown that FSTL1 acts as a muscle-derived secreted factor that is up-regulated by Akt activation and ischemic stress and that FSTL1 exerts favorable actions on the heart and vasculature. Here, we sought to identify the receptor that mediates the cellular actions of FSTL1. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. FSTL1 is thought to be an autoantigen associated with rheumatoid arthritis. DIP2A functions as a novel receptor that mediates the cardiovascular protective effects of FSTL1. Experiment results have provided in vivo and in vitro evidence to demonstrate that Fstl1 modulates lung development and alveolar maturation, in part, through BMP4 signaling.
NCBI Accession NP_009016.1
研究領域 Cardiovascular, Atherosclerosis

使用細節(jié)

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使用細節(jié)

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應用備注 ELISA ELISA: 0.5-1.0 μg/mL This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Human FSTL1. The detection limit for Human FSTL1 is 0.039 ng/well.
限制 For Research Use only

貯存及處理

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貯存及處理

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緩沖液 PBS with 5% trehalose
儲存液 Without preservative
注意事項 Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
儲存條件 4 °C/-20 °C/-80 °C
儲存方法 This antibody can be stored at 2 °C-8 °C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 °C to -70 °C.
有效期 12 months

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