C1ORF170抗體

抗原
Chromosome 1 Open Reading Frame 170 (C1ORF170)
別名 RP11-54O7.8
適用
其他選擇 Human, Murine, Rat ((Rattus)), Bovine
Bovine(11),Human (11),Murine (11),Rat ((Rattus)) (11)
宿主
其他選擇 Rabbit
Rabbit(11)
克隆類型
多克隆
標(biāo)記
其他選擇 Cy5
Alexa Fluor 350(1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Biotin (1),Cy3 (1),Cy5.5 (1),Cy7 (1),FITC (1),HRP (1)
應(yīng)用范圍
其他選擇 Immunofluorescence (Paraffin-embedded Sections) (IF (p))
Immunofluorescence (Paraffin-embedded Sections) (IF (p))(9),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3),Western Blotting (WB) (3)
規(guī)格 100 μL
發(fā)貨至 中國 (更改)

C1ORF170抗體

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
免疫原 KLH conjugated synthetic peptide derived from human C1orf170
亞型 IgG
交叉反應(yīng) Murine, Rat ((Rattus)), Bovine
純化方法 purified by Protein A

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 C1orf170
背景 Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf170 gene product has been provisionally designated C1orf170 pending further characterization. There are two isoforms of C1orf170 that are produced as a result of alternative splicing events.

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使用細(xì)節(jié)

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應(yīng)用備注 IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.
說明

Excitation / Emission wavelength: 652nm / 670nm

限制 For Research Use only

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貯存及處理

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狀態(tài) Liquid
濃度 1 μg/μL
緩沖液 Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
儲存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲存條件 4 °C

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