5-羥色胺受體1D抗體

英文名稱 5HT1D Receptor
中文名稱 5-羥色胺受體1D抗體
別    名 SR-1D; 5 HT 1D alpha; 5 HT 1D; 5 HT1B; 5 HT1D; 5HT1D; 5 hydroxytryptamine (serotonin) receptor 1B; 5 hydroxytryptamine (serotonin) receptor 1D G protein coupled; 5 hydroxytryptamine 1B receptor (5 HT 1B) (Serotonin receptor) (5 HT 1D beta) (Serotonin 1D beta receptor) (S12); 5 hydroxytryptamine receptor 1D; HT1DA; HTR1D; HTR1D2; HTR1DA; HTRL; RDC4; S12; Serotonin receptor 1D; 5HT1D_HUMAN.

說 明 書 0.2ml  
研究領域 神經生物學  細胞膜受體  G蛋白偶聯(lián)受體  新陳代謝  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Rabbit, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 42kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human 5HT1D Receptor/SR-1D
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic bound to adrenaline activates adenylyl cyclase, while a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the a2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-1–7 (5HT1–7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.

Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.

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