花生四烯酸15脂氧合酶2抗體

英文名稱 15 Lipoxygenase 2
中文名稱 花生四烯酸15脂氧合酶2抗體
別    名 15 LO 2; 15 LOX 2; 15-lipoxygenase 2; 15-LOX-2; 15-LOX-B; ALOX15B; Arachidonate 15 lipoxygenase second type; Arachidonate 15 lipoxygenase type II; Arachidonate 15-lipoxygenase B; Arachidonate 15-lipoxygenase type II; LX15B_HUMAN.
花生四烯酸15脂氧合酶2抗體
說 明 書   
研究領(lǐng)域 腫瘤  心血管  細胞生物  信號轉(zhuǎn)導(dǎo)  細胞凋亡  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 76kDa
細胞定位 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human 15 Lipoxygenase 2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
花生四烯酸15脂氧合酶2抗體
PubMed PubMed
產(chǎn)品介紹 background:
Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes, the synthesis of signalling molecules as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals, 12-LO and 15-LO, are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation. 15-lipoxygenase, type II (15-LO2) is important for the conversion of arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid. It is a cytoplasmic protein expressed primarily in cornea, lung, hair and prostate.花生四烯酸15脂氧合酶2抗體xy-1959R    IL2 Receptor beta白介素2受體β鏈抗體 IL-2Rβ
xy-0536R    Interferon alpha 2b干擾素α2b抗體
xy-2471R    ICOS ligand誘導(dǎo)協(xié)同刺激分子配體CD275抗體
xy-10050R    IBDV雞傳染性法氏囊病病毒抗體
xy-2140R    IL-17白介素-17抗體
xy-5924R    IMPDH25'肌苷磷酸脫氫酶2抗體
xy-15545R    IER5L即刻早期應(yīng)答基因5樣蛋白抗體
xy-2250R    CD51整合素αV抗體
xy-2618R    IL-19/NG.1白細胞介素-19抗體
xy-2598R    IL-3白介素3抗體
xy-2600R    IL-3R alpha/CD123白介素3受體a鏈抗體
xy-2601R    IL5RA/CD125白介素-5受體α鏈抗體IL-5Rα
xy-2602R    IL-10RB/CRFB4白細胞介素-10受體β抗體
xy-2603R    IL-12RB1/CD212白細胞介素-12受體β1抗體
xy-2604R    IL12RB2白細胞介素-12受體β2抗體
xy-2605R    IL-15RA白介素15受體α抗體
xy-2606R    IL-17R/IL-17RA/CD217白介素17受體抗體
xy-2610R    IL-17RB白介素-17B受體抗體
xy-2616R    IL-18R Beta/IL1R7/CD218b白細胞介素-18受體β鏈抗體
xy-2621R    IL-21白介素21抗體
xy-2622R    IL-21R白介素21受體抗體
xy-2623R    IL-22白介素-22抗體
xy-2629R    IL-29/IFNL1白細胞介素29抗體
xy-2625R    IL-22BP/IL22RA2白介素22受體結(jié)合蛋白抗體
xy-2440R    IRAK4白介素-1受體相關(guān)激酶4抗體
xy-2500R    IRF4干擾素調(diào)節(jié)因子4抗體
xy-6457R    IGF-I Receptor beta胰島素樣生長因子1受體β/IGF-IRβ 抗體
xy-10492R    ING4ING4抗體
xy-10491R    rat IgA大鼠血清型IgA抗體
xy-2614R    MDA7/IL-24/IL-17F白介素-17F抗體
xy-15570R    IGFL1胰島素生長因子樣家族成員1抗體
xy-2611R    IL-17C白介素-17C抗體
xy-2985R    ADM2中介素抗體
xy-10246R    IkB betaNF-kappa-B抑制子beta抗體