硫氧還蛋白還原酶抗體

英文名稱 Peroxiredoxin 4
中文名稱 硫氧還蛋白還原酶抗體
別    名 2 Cys Peroxiredoxin; ACR 1; ACR1; Alu co repressor 1; Alu co-repressor 1; Alu corepressor 1; Antioxidant enzyme; Antioxidant enzyme B166; AOEB 166; AOEB166; B166; Liver tissue 2D page spot 71B; MGC117264; MGC142283; MGC142285; Peroxiredoxin 1; Peroxiredoxin 2; Peroxiredoxin 3; Peroxiredoxin 4; Peroxiredoxin 5; Peroxiredoxin 5 mitochondrial; Peroxiredoxin5; Peroxisomal antioxidant enzyme; PLP; PMP 20; PMP20; PRDX 5; PRDX 6; PRDX1; PRDX2; PRDX3; PRDX4; PRDX5; PRDX6; PRX V; PRXV; SBBI 10; SBBI10; Thioredoxin peroxidase PMP20; Thioredoxin reductase; TPx type VI; PRDX5_HUMAN.
  
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  細(xì)胞凋亡  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Horse, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 17kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human 2 Cys Peroxiredoxin
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Peroxiredoxin (Prx) is a growing peroxidase family whose mammalian members are involved in cell proliferation, differentiation, and apoptosis. There are many isoforms(about 50 proteins), known on the basis of amino acid sequence homology, particularly the amino-terminal region containing an active site cysteine residue. The thiol-specific antioxidant activity is distributed throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2 Cys, atypical 2 Cys Prx, and 1 Cys Prx. Except PrxVI belonging to the 1 Cys Prx subgroup, the other five 2 Cys Prx isotypes share the thioredoxin dependent peroxidase(TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20–30 kilodaltons in molecular size and vary in subcellular localization:PrxI, II and VI in cytosol, PrxIII in mitochondria, PrxIV in ER and secretion, PrxV showing complicated distribution including peroxisome, mitochondria and cytosol.

Subcellular Location:
Cytoplasmic and Mitochondrial

Gene ID:
10549xy-13592R    IRF6干擾素調(diào)節(jié)因子6抗體
xy-7176R    IQGAP2
xy-15572R    IGFL4胰島素生長(zhǎng)因子樣家族成員4抗體
xy-10070R    IL-31白細(xì)胞介素31抗體
xy-10061R    IFI78干擾素誘導(dǎo)蛋白P78抗體
xy-10237R    Inhibin Alpha抑制素α/Inhibin α抗體
xy-4988R    IL-18白介素18抗體
xy-3621R    eIF4E真核翻譯起始因子4E抗體
xy-7712R    Importin4核蛋白4抗體（Ran結(jié)合蛋白4）
xy-4678R    IgHV免疫球蛋白重鏈可變區(qū)抗體
xy-5098R    IGFBP7胰島素樣生長(zhǎng)因子結(jié)合蛋白7抗體
xy-4064R    IGFBP6胰島素樣生長(zhǎng)因子結(jié)合蛋白6抗體
xy-4139R    IKB epsilonKB抑制蛋白激酶ε
xy-4115R    ITGB4整合素β4抗體
xy-5395R    phospho-IL-7Ra(Tyr449)磷酸化白細(xì)胞介素-7受體a抗體
xy-5396R    phospho-IRS1(Ser312)磷酸化胰島素受體底物-1抗體
xy-5397R    phospho-IRS-2(Ser731)磷酸化胰島素受體底物2抗體
xy-5398R    phospho-IKK beta(Ser471)磷酸化KB抑制蛋白激酶β抗體
xy-5399R    phospho-IKK beta(Ser740)磷酸化KB抑制蛋白激酶β抗體
xy-5440R    phospho-IKK beta(Ser733)磷酸化KB抑制蛋白激酶β抗體
xy-5441R    phospho-IKK beta(S474)磷酸化KB抑制蛋白激酶β抗體
xy-5442R    phospho-IKK beta(Ser476)磷酸化KB抑制蛋白激酶β抗體
xy-5443R    phospho-ILK-1(Thr173)磷酸化整合素連接激酶1抗體
xy-5444R    phospho-ILK-1(Ser246) 磷酸化整合素連接激酶1抗體
xy-5445R    phospho-ILK-1(Ser259)磷酸化整合素連接激酶1抗體
xy-5446R    phospho-IRS1(Thr176)磷酸化胰島素受體底物1抗體
xy-5450R    phospho-ICAM1(Tyr512)磷酸化細(xì)胞間粘附分子1抗體
xy-5452R    phospho-ITGB3(Tyr785)磷酸化整合素β3抗體
xy-5447R    phospho-IGF1R (Tyr980)磷酸化胰島素樣生長(zhǎng)因子1受體抗體
xy-5448R    phospho-IGF1R (Tyr1280)磷酸化胰島素樣生長(zhǎng)因子1受體抗體
xy-5449R    phospho-IGF1R (Tyr1165 + Tyr1166)磷酸化胰島素樣生長(zhǎng)因子1受體抗體
xy-5451R    phospho-ITGB3(Tyr773)磷酸化整合素β3抗體
xy-15574R    IGIP免疫球蛋白A誘導(dǎo)同源蛋白抗體
xy-4586R    IL-2白介素2抗體
xy-4586M    IL-2白介素2抗體