跨膜蛋白SEMA4G抗體

英文名稱 SEMA4G
中文名稱 跨膜蛋白SEMA4G抗體
別    名 SEM4G_HUMAN; sema domain immunoglobulin domain (Ig) transmembrane domain (TM) and short cytoplasmic domain (semaphorin) 4G; Sema4g; semaphorin 4G; Semaphorin 4G precursor; Semaphorin-4G.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  細(xì)胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Horse, 
產(chǎn)品應(yīng)用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 90kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SEMA4G (71-120aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the
PubMed PubMed
產(chǎn)品介紹 background:
Semaphorins are a family of cell surface and secreted proteins that are conserved from insects to humans. Members of this family of proteins are approximay 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular “semaphorin" domain of approximay 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. Secreted and cell-bound semaphorins chemically attract and repel the growth of neural axons, guiding the development of intricate networks of neural tissue. SEMA4G (semaphorin-4G) is an 838 amino acid single-pass type I membrane protein that is thought to play a role in axon guidance. Existing as three alternatively spliced isoforms, SEMA4G contains one Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a single SEMA domain.

Function:
Cell surface receptor for PLXNB2. May play a role in axon guidance.

Subunit:
Interacts with PLXNB2

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.xy-4660R    phospho-MARK4(Ser423)磷酸化絲氨酸/蘇氨酸蛋白激酶MARK4抗體
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