絲氨酸/蘇氨酸蛋白激酶2抗體

英文名稱 STK2
中文名稱 絲氨酸/蘇氨酸蛋白激酶2抗體
別    名 CTCL tumor antigen se20 9; LOSK; se20 9; Serine/threonine protein kinase 2; STK2; SLK; SNF1 sucrose nonfermenting like kinase; STE20 like serine/threonine-protein kinase; STE20 related kinase; STK2; SLK_HUMAN.

說(shuō) 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  激酶和磷酸酶  細(xì)胞骨架  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Horse, Rabbit, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 143kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human STK2 (885-931aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
SLK is a member of the serine/threonine kinase subfamily, Ste20. This subfamily is comprised of several mammalian kinases which exhibit sequence similarity to the Saccharomyces cerevisiae serine/threonine kinase Ste20, a protein involved in relaying signals from G protein-coupled receptors to cytosolic MAP kinase cascades. Members of this subfamily include KHS, GLK, YSK1, HPK1, Krs-1, Krs-2, GC kinase, HGK and SLK. SLK is a ubiquitously expressed protein that localizes to the cytoplasm and contains an N-terminal protein kinase domain, a central coiled-coil domain and a C-terminal ATH domain. SLK is activated through cleavage by caspase-3. SLK indirectly associates with microtubules and plays an important role in cellular stress, cell motility, cell death and cytoskeletal dynamics.

Function:
SLK is a serine/threonine protein kinase that is involved in cytoskeletal reorganization and apoptosis. SLK is a microtubule-associated protein inducing actin stress fiber disassembly, it also mediates apoptosis and it is ubiquitously expressed; highest expression is found in heart and in skeletal muscle. There are two named isoforms.

Subcellular Location:
Cytoplasmicxy-11890R    Monoamine oxidase A+B單氨氧化酶A+B抗體
xy-12039R    MIR16膜蛋白相互作用蛋白R(shí)GS16抗體
xy-8296R    Matriptase 2膜型絲氨酸蛋白酶2抗體
xy-7870R    MRP8+MRP14多藥耐藥相關(guān)蛋白8/9/14抗體
xy-7914R    MOBKL2BMob1同源蛋白MOBKL2B抗體
xy-7915R    MOBKL2CMob1同源蛋白MOBKL2C抗體
xy-7880R    MEGF5復(fù)合型表皮生長(zhǎng)因子樣結(jié)構(gòu)域蛋白5抗體
xy-9674R    MYLIP低密度脂蛋白受體的誘導(dǎo)降解蛋白抗體
xy-9673R    ZNF144鋅指蛋白144抗體
xy-6936R    MYF5生肌決定因子Myf5抗體
xy-8200R    phospho-MYF5 (phospho Ser49)磷酸化生肌決定因子Myf5抗體
xy-11419R    MRAP2黑素皮質(zhì)素2受體輔助蛋白2抗體
xy-4940R    Metallothionein 3金屬硫蛋白3抗體
xy-9109R    MAP4K6 絲裂原活化蛋白激酶MAP4K6抗體
xy-0266R    MAP65擬南芥MAP65蛋白抗體
xy-11201R    Musashi 1神經(jīng)干細(xì)胞RNA結(jié)合蛋白Musashi1抗體
xy-11179R    MAdCAM1粘膜細(xì)胞粘附分子1抗體
xy-4943R    MPO髓過(guò)氧化物酶抗體
xy-11352R    MAGI1膜相關(guān)鳥(niǎo)苷酸反轉(zhuǎn)激酶1抗體
xy-11353R    Munc13 神經(jīng)突觸前膜胞內(nèi)蛋白13抗體
xy-11322R    Membralin高度保守基因相關(guān)蛋白Membralin抗體
xy-11320R    MNX1運(yùn)動(dòng)神經(jīng)元及胰腺同源蛋白1抗體
xy-11184R    MOBP少突膠質(zhì)細(xì)胞髓鞘相關(guān)蛋白抗體
xy-11189R    MRCK alphaCDC42結(jié)合蛋白激酶α抗體（MRCKα）
xy-1047R    MyD88髓樣分化蛋白抗體
xy-0337R    Myelin Protein Zero外周髓磷脂P0蛋白/P0蛋白抗體
xy-0027R    Melatonin Receptor 1A褪黑素受體1A/松果體素受體1A抗體
xy-3550R    Myogenin肌細(xì)胞生成素抗體
xy-3296R    Phospho-Myt1(Ser83)磷酸化髓鞘轉(zhuǎn)錄因子1抗體
xy-3503R    Mre11DNA損傷關(guān)鍵蛋白Mre11抗體
xy-3293R    Phospho-Mre11 (Ser676)磷酸化DNA損傷關(guān)鍵蛋白Mre11抗體
xy-3504R    MST1蛋白激酶MST抗體
xy-3294R    Phospho-Mst1(Thr183) + Mst2(Thr180)磷酸化蛋白激酶MST抗體
xy-3295R    Phospho-MYL(Ser19)磷酸化肌球蛋白輕鏈2抗體
xy-3505R    Myt1髓鞘轉(zhuǎn)錄因子1抗體
xy-1352R    MCL1髓樣細(xì)胞白血病-1抗體
xy-1369R    MAP2微管相關(guān)蛋白2抗體
xy-9470R    MEF2B肌細(xì)胞增強(qiáng)因子2B抗體