精子相關蛋白16抗體

英文名稱 SPAG16
中文名稱 精子相關蛋白16抗體
別    名 PF20; pf20 protein homolog; sperm associated antigen 16; sperm associated WD repeat protein; WD repeat domain 29; WRD29; SPG16_HUMAN.
 
說 明 書 0.1ml  0.2ml  
研究領域 細胞生物  發(fā)育生物學  神經(jīng)生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
細胞定位 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SPAG16
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Cilia and flagella are comprised of a microtubular backbone, the axoneme, which is organized by the basal body and surrounded by plasma membrane. SPAG16 encodes 2 major proteins that associate with the axoneme of sperm tail and the nucleus of postmeiotic germ cells, respectively (Zhang et al., 2007 [PubMed 17699735]).[supplied by OMIM, Jul 2008]

Function:
Necessary for sperm flagellar function. Plays a role in motile ciliogenesis. May help to recruit STK36 to the cilium or apical surface of the cell to initiate subsequent steps of construction of the central pair apparatus of motile cilia

Subunit:
Interacts with SPAG6 and STK36

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm, cytoskeleton, cilium axoneme. Note=Detected on the sperm flagellum axoneme. Detected in the central apparatus of the axoneme. Colocalizes with SPAG6 on microtubules.

Tissue Specificity:
Isoform 1 is detected in testis. Isoform 4 is detected in testis and brain, and at lower levels in kidney, heart, pancreas, thyroid, ovary, adrenal gland, spinal cord, trachea and liver.

Post-translational modifications:
Phosphorylated by TSSK2xy-5427R    phospho-MEK2(Thr394)磷酸化絲裂原活化蛋白激酶激酶2抗體
xy-4123R    phospho-MEK3(Thr222)磷酸化絲裂原活化蛋白激酶激酶3抗體
xy-4124R    MEK5絲裂原活化蛋白激酶激酶5抗體
xy-5429R    phospho-MEK5(Ser142)磷酸化絲裂原活化蛋白激酶激酶5抗體
xy-5430R    phospho-MEK5(Ser311+Thr315)磷酸化絲裂原活化蛋白激酶激酶5抗體
xy-5431R    phospho-MEK5(Ser129)磷酸化絲裂原活化蛋白激酶激酶5抗體
xy-5432R    phospho-MEK5(Ser137)磷酸化絲裂原活化蛋白激酶激酶5抗體
xy-4186R    MIG5細胞遷移誘導因子5抗體
xy-0334R    MTLC致癌基因抗體
xy-13654R    MAP4K5絲裂原活化蛋白激酶MAP4K5抗體
xy-13655R    MKLN1MKLN1抗體
xy-13688R    MAP2K1IP1絲裂原活化蛋白激酶相互作用蛋白1抗體
xy-13689R    MPP2MPP2蛋白抗體
xy-13690R    MS4A14睪丸發(fā)育相關蛋白抗體
xy-13691R    MS4A15MS4A15蛋白抗體
xy-13692R    MS4A6A四度跨膜蛋白3抗體
xy-6818R    MAGEA12黑色素瘤相關抗原12抗體
xy-6819R    MAGEA2黑色素瘤相關抗原2抗體
xy-6820R    MAGEA5黑色素瘤相關抗原5抗體
xy-10158R    Msx2同源盒基因Msx2抗體
xy-5470R    Phospho-MDM2(Thr218)磷酸化雙微體2癌基因抗體
xy-5471R    Phospho-MDM2(Ser186)磷酸化雙微體2癌基因抗體
xym-2182M    Melamine(1B12)三聚氰胺單克隆抗體
xy-6821R    MAGEB1黑色素瘤相關抗原B1抗體
xy-2721R    MCM5微小染色體維持缺陷蛋白5抗體
xy-4293R    MACC1結腸癌轉(zhuǎn)移相關蛋白1抗體
xy-4597R    MMP-1基質(zhì)金屬蛋白酶-1抗體
xy-5483R    phospho-MEF2C(Thr300)磷酸化肌細胞增強因子2C抗體
xy-5485R    Phospho-MEF2A(Thr319)磷酸化肌細胞增強因子2抗體
xy-5474R    phospho-MBP(Thr232)磷酸化髓鞘堿性蛋白抗體
xy-5475R    phospho-MBP(Tyr203)磷酸化髓鞘堿性蛋白抗體
xy-5478R    phospho-MYL6(Tyr29+Ser30)磷酸化肌球蛋白輕鏈6抗體