雙鏈RNA結(jié)合蛋白Staufen2抗體

英文名稱 STAU2
中文名稱 雙鏈RNA結(jié)合蛋白Staufen2抗體
別    名 Double stranded RNA binding protein Staufen homolog 2; MGC119606; STAU 2; STAU2; STAU-2; Staufen (Drosophila, RNA-binding protein) homolog 2; Staufen homolog 2; Staufen RNA binding protein homolog 2; Staufen, RNA binding protein, homolog 2 (Drosophila); 39K2; 39K3; DKFZp781K0371; STAU2_HUMAN.

說 明 書 0.2ml  
研究領(lǐng)域 神經(jīng)生物學(xué)  細胞粘附分子  細胞骨架  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Horse, Rabbit, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 63kDa
細胞定位 細胞核 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human STAU2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

產(chǎn)品介紹 background:
Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48.5% and 59.9% similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene. 

Function:
RNA-binding protein required for the microtubule-dependent transport of neuronal RNA from the cell body to the dendrite. As protein synthesis occurs within the dendrite, the localization of specific mRNAs to dendrites may be a prerequisite for neurite outgrowth and plasticity at sites distant from the cell body (By similarity). 

Subunit:
Interacts with the exportin XPO5. This requires RNA and RAN bound to GTP. Interacts with microtubules. Isoform 2 and isoform 3 may also interact with ribosomes, and this association is independent of translation (By similarity). Identified in a mRNP complex, at least composed of DHX9, DDX3X, ELAVL1, HNRNPU, IGF2BP1, ILF3, PABPC1, PCBP2, PTBP2, STAU1, STAU2, SYNCRIP and YBX1. xy-5650R    phospho-c-Raf(Tyr341)磷酸化原癌基因c-Raf抗體
xy-5651R    phospho-c-Raf(Thr269)磷酸化原癌基因c-Raf抗體
xy-5652R    phospho-c-Raf(Ser339)磷酸化原癌基因c-Raf抗體
xy-5653R    Phospho-Rb (Ser612)磷酸化視網(wǎng)膜母細胞瘤相關(guān)蛋白1抗體
xy-5665R    Phospho-P105 RB (Ser788)磷酸化視網(wǎng)膜母細胞瘤相關(guān)蛋白1抗體
xy-5668R    phospho-RPS6KB1(Ser417)磷酸化核糖體S6蛋白激酶抗體
xy-5670R    phospho-RPS6KB1(Ser427)磷酸化核糖體S6蛋白激酶抗體
xy-5666R    Phospho-Rb (Ser795)磷酸化視網(wǎng)膜母細胞瘤相關(guān)蛋白1抗體
xy-5667R    Phospho-Rb (Thr826)磷酸化視網(wǎng)膜母細胞瘤相關(guān)蛋白1抗體
xy-5669R    phospho-RPS6KB1(Thr 412) 磷酸化核糖體S6蛋白激酶抗體
xy-5671R    phospho-RPS6KB1(Ser434)磷酸化核糖體S6蛋白激酶抗體
xy-5672R    phospho-RPS6KB1(Ser421)磷酸化核糖體S6蛋白激酶抗體
xy-5673R    phospho-RPS6KB1(Ser441+Thr444)磷酸化核糖體S6蛋白激酶抗體
xy-5674R    phospho-ROCK2(Thr396)磷酸化Rho相關(guān)蛋白激酶2抗體
xy-5675R    phospho-ROCK2(Thr249)磷酸化Rho相關(guān)蛋白激酶2抗體
xy-5676R    phospho-ROCK2(Tyr256)磷酸化Rho相關(guān)蛋白激酶2抗體
xy-5686R    phospho-RGS19(Ser22)磷酸化G蛋白信號轉(zhuǎn)導(dǎo)調(diào)節(jié)因子19抗體
xy-5677R    phospho-RAD51(Thr309)磷酸化Rad51抗體
xy-5678R    Phospho-RSK2(Ser369)磷酸化核糖體S6激酶RSK2抗體
xy-5679R    phospho-RPS6KA1(Thr359)磷酸化絲氨酸/蘇氨酸激酶p90RSK蛋白抗體
xy-5680R    phospho-RPS6KA1(Thr348)磷酸化磷酸化絲氨酸/蘇氨酸激酶p90RSK蛋白抗體
xy-5681R    phospho-RPS6KA1(Ser363)磷酸化絲氨酸/蘇氨酸激酶p90RSK蛋白抗體
xy-5902R    RBM3RNA結(jié)合基因蛋白3抗體
xy-6175R    RAB5ras癌基因家族Rab5蛋白抗體
xy-6173R    Rab11ras癌基因家族Rab11蛋白抗體
xy-6182R    RBP4視黃醇結(jié)合蛋白4抗體
xy-6183R    REG1A胰島細胞再生因子ICRF抗體
xy-6184R    Renin腎素/血管緊張素形成酶Ren1抗體
xy-6185R    RSPO1分泌性蛋白RSPO1抗體
xy-6171R    RASA2RAS的GTP酶激活蛋白抗體
xy-6153R    RAC2G蛋白P21 RAC2抗體