SHFM3蛋白抗體

英文名稱 SHFM3
中文名稱 SHFM3蛋白抗體
別    名 DAC; Dactylin; F box and WD 40 domain containing protein 4; F box and WD 40 domain protein 4; F box and WD repeat domain containing 4; F box/WD repeat containing protein 4; F box/WD repeat protein 4; F-box and WD-40 domain-containing protein 4; F-box/WD repeat-containing protein 4; FBW 4; FBW4; FBWD 4; FBWD4; FBXW 4; FBXW4; FBXW4_HUMAN; SHFM 3; SHSF 3; SHSF3; Split hand/foot malformation (ectrodactyly) type.
   
說 明 書 0.2ml  
研究領域 細胞生物  發(fā)育生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, 
產(chǎn)品應用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SHFM3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling.
Involvement in disease:Defects in FBXW4 are a cause of split-hand/foot malformation type 3 (SHFM3) . SHFM3 is an autosomal dominant disorder characterized by hypoplasia/aplasia of the central digits with fusion of the remaining digits.

Function:
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling. xy-13557R    ZBT24鋅指蛋白450抗體
xy-13560R    ZA20D3鋅指蛋白20D3抗體
xy-13553R    ZBED3鋅指蛋白BED3抗體
xy-13572R    ZBTB38鋅指蛋白ZBTB38抗體
xy-13562R    ZADH2鋅結合乙醇脫氫酶結構域蛋白2抗體
xy-13567R    ZBTB3鋅指蛋白ZBTB3抗體
xy-13551R    ZBBX鋅指蛋白ZBBX抗體
xy-12253R    ZFP219鋅指蛋白219抗體
xy-12254R    ZFP36L1EGF應答因子1抗體抗體
xy-12255R    phospho-ZFP36L1(Ser334)磷酸化鋅指蛋白36抗體
xy-12240R    ZNF347鋅指蛋白347抗體
xy-13555R    ZBED5鋅指蛋白BED5抗體
xy-12241R    ZNF704鋅指蛋白704抗體
xy-13586R    ZNF434宮頸癌抑癌蛋白5/鋅指蛋白434抗體
xy-0354R    ZCWCC1ZCWCC1抗體
xy-0628R    ZNF300鋅指蛋白300抗體
xy-13573R    ZBTB39鋅指蛋白ZBTB39抗體
xy-11609R    Zic1鋅指蛋白201抗體
xy-11610R    Zic2鋅指蛋白Zic2抗體
xy-8641R    ZDHHC-18鋅指蛋白Zdhhc18抗體
xy-6958R    ZDHHC-12鋅指蛋白Zdhhc12抗體
xy-7852R    ZWINT著絲粒ZW10相互作用蛋白1抗體
xy-9139R    ZNRF1鋅指/環(huán)指蛋白1抗體
xy-9140R    ZNRF2鋅指/環(huán)指蛋白2抗體
xy-9141R    ZNRF3鋅指蛋白3/環(huán)指蛋白3抗體
xy-9143R    ZNF230鋅指蛋白230抗體
xy-0626R    ZNF268鋅指脂蛋白-1b抗體
xy-1942R    ZAP70zeta相關蛋白70抗體
xy-1941R    Zfp91白血病相關新基因抗體
xy-1940R    ZNF307鋅指蛋白307抗體
xy-1937R    Zyxin斑聯(lián)蛋白抗體
xy-1939R    ZNF474鋅指蛋白474抗體
xy-13554R    ZBED4鋅指蛋白BED4抗體