5脂氧合酶激活蛋白抗體

英文名稱 FLAP
中文名稱 5脂氧合酶激活蛋白抗體
別    名 5-lipoxygenase activating protein; Arachidonate 5 lipoxygenase activating protein; 5-lipoxygenase activating protein; AL5AP_HUMAN; ALOX 5AP; ALOX5 AP; ALOX5AP; Arachidonate 5-lipoxygenase-activating protein; Five lipoxygenase activating protein; FLAP; MK 886 binding protein; MK-886-binding protein.
  
說 明 書 0.2ml  
研究領(lǐng)域 心血管  細胞生物  免疫學  信號轉(zhuǎn)導  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Pig, Cow, Horse, Rabbit, Sheep, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 18kDa
細胞定位 細胞核 細胞漿 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human FLAP/5-lipoxygenase activating protein
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.
Involvement in disease: Genetic variations in ALOX5AP may be a cause of susceptibility to ischemic stroke (ISCHSTR) ; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.xy-6423R    PI3 Kinase p110 beta磷脂酰肌醇激酶（PI3Kβ）抗體
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xy-8064R    PLEKHM3血小板白細胞C激酶底物同源結(jié)構(gòu)域M3抗體
xy-2138R    PARP多腺苷二磷酸多聚酶抗體(N端)
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xy-11112R    PCDH18原鈣粘附蛋白18抗體
xy-11113R    PCDH20原鈣粘附蛋白20抗體
xy-11114R    PCDH8原鈣粘附蛋白8抗體
xy-6371R    Protamine 2魚精蛋白2抗體
xy-6853R    PIWIL4piwi樣4蛋白抗體
xy-6348R    PIWIL3piwi樣3蛋白抗體
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xy-6847R    PDCD10凋亡相關(guān)蛋白10抗體
xy-7595R    PPM1F鈣調(diào)蛋白依賴性蛋白激酶磷酸酶抗體
xy-4852R    PIM3絲氨酸/蘇氨酸蛋白激酶PIM3抗體
xy-6992R    PRMT5組蛋白精氨酸甲基轉(zhuǎn)移酶5抗體
xy-11107R    PCDH11X原鈣粘附蛋白11X抗體
xy-11108R    PCDH11Y原鈣粘附蛋白11Y抗體
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xy-11110R    PCDH17原鈣粘附蛋白17抗體
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xy-11117R    PCDHA3原鈣粘附蛋白α3抗體
xy-11118R    PCDHA4原鈣粘附蛋白α4抗體
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