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當(dāng)前位置:上海信裕生物科技有限公司>>抗體>>一抗>> 鈉碘轉(zhuǎn)運(yùn)體蛋白8抗體
產(chǎn)品型號
品 牌Abcam
廠商性質(zhì)生產(chǎn)商
所 在 地上海
更新時間:2015-06-01 14:23:42瀏覽次數(shù):404次
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英文名稱 SLC5A8
中文名稱 鈉碘轉(zhuǎn)運(yùn)體蛋白8抗體
別 名 AIT; Apical iodide transporter; Electrogenic sodium monocarboxylate cotransporter; SC5A8_HUMAN; SLC5A8; SMCT; SMCT1; sodium coupled monocarboxylate transporter 1; Sodium iodide related cotransporter; Sodium iodide-related cotransporter; Sodium-coupled monocarboxylate transporter 1; solute carrier family 5 iodide transporter member 8; Solute carrier family 5 member 8.
說 明 書 0.1ml 0.2ml
研究領(lǐng)域 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 細(xì)胞凋亡
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Cow,
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 67kDa
細(xì)胞定位 細(xì)胞膜
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC5A8
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
產(chǎn)品介紹 background:
Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. Acts as a tumor suppressor, suppressing colony formation in colon cancer, prostate cancer and glioma cell lines. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons.xy-0741R CDKN1Ap21蛋白抗體
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xy-1199R PAX1配對盒基因1抗體
xy-1187R PAX2配對盒基因2抗體
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xy-6966R p47-phoxNADPH氧化酶活化蛋白p47抗體
xy-9349R Proteasome 19S S7蛋白酶體PRS7抗體
xy-9350R Proteasome 20S C2蛋白酶體PSMα1抗體
xy-9351R Proteasome 20S alpha 2蛋白酶體PSMα2抗體
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xy-9356R PSMA7蛋白酶體PSMα7抗體
xy-9612R PIBF1孕酮誘導(dǎo)阻斷因子1抗體
xy-9623R PARP16多腺苷二磷酸多聚酶16抗體
xy-9605R PITX2成對樣同源結(jié)構(gòu)域轉(zhuǎn)錄因子2抗體
xy-6972R RNA polymerase IIRNA聚合酶II抗體
xy-1364R PHLDA1T淋巴細(xì)胞凋亡相關(guān)蛋白TDAG51抗體
xy-1372R PSMD9蛋白酶調(diào)解因子9抗體
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xy-9844R PLGLB2纖溶酶相關(guān)蛋白B2抗體
xy-9435R PAPOL A+B+G多聚合酶α/β/γ抗體
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