調(diào)控周期蛋白依賴蛋白激酶SEI1抗體

英文名稱 Sertad1
中文名稱 調(diào)控周期蛋白依賴蛋白激酶SEI1抗體
別    名 CDK 4 binding protein p34SEI1; CDK4 binding protein p34SEI; CDK4 binding protein p34SEI1; SEI 1; SEI1; SERTA domain containing 1; SERTA domain containing 1 variant; SERTA domain containing protein 1; Sertad 1; Transcriptional regulator interacting with the PHD bromodomain 1; TRIP Br1; SRTD1_HUMAN.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SEI1 (1-35aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the
PubMed PubMed
產(chǎn)品介紹 background:
Sertad1 acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F-1/DP-1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of p16(INK4a).

Function:
Acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F-1/DP-1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of p16(INK4a).

Subunit:
Interacts with the PHD-bromodomain of TIF1, TRIM28/TIF1B and p300/CBP. Binds to DP1. Also interacts with CDK4.

Similarity:
Contains 1 SERTA domain.

Database links:
 

UniProtKB/Swiss-Prot: Q9UHV2.2xy-8497R    RENBP腎素結(jié)合蛋白抗體
xy-8493R    RFPL2+RFPL3RET指蛋白樣2/3抗體
xy-8496R    RFESDRFESD蛋白抗體
xy-8498R    REG1 beta胰島細(xì)胞再生因子β抗體
xy-8376R    RNF160環(huán)指蛋白160抗體
xy-8333R    RDH13視黃醇脫氫酶13抗體
xy-8391R    RNF75環(huán)指蛋白75抗體
xy-8392R    RIT1RIT1蛋白抗體
xy-9246R    RNF19B環(huán)指蛋白19B抗體
xy-8509R    Reg3a胰島β細(xì)胞生長因子抗體
xy-9228R    RNF149環(huán)指蛋白149抗體
xy-9230R    RNF158心臟蛋白磷酸酶1結(jié)合蛋白/環(huán)指蛋白158抗體
xy-9233R    RNF180環(huán)指蛋白180抗體
xy-9249R    RNF123環(huán)指蛋白123抗體
xy-8499R    RED軟骨肉瘤相關(guān)蛋白2抗體
xy-8494R    RNF210環(huán)指蛋白210抗體
xy-9238R    RNF23環(huán)指蛋白23抗體
xy-9239R    RNF24環(huán)指蛋白24抗體
xy-9240R    RNF25環(huán)指蛋白25抗體
xy-9241R    RNF31環(huán)指蛋白31抗體
xy-9242R    RNF34環(huán)指蛋白34抗體
xy-9244R    RNF21環(huán)指蛋白21抗體
xy-9245R    RNF190環(huán)指蛋白190抗體
xy-11355R    RIC8A膽堿酯酶抑制劑8抗體
xy-11356R    ABCA4神經(jīng)元突觸膜胞外分泌調(diào)節(jié)蛋白1抗體
xy-11357R    RIM2神經(jīng)元突觸膜胞外分泌調(diào)節(jié)蛋白2抗體
xy-9252R    RNF130環(huán)指蛋白130抗體
xy-9609R    RBM26RNA結(jié)合蛋白26抗體
xy-9265R    RNF32環(huán)指蛋白32抗體
xy-6872R    RING finger protein 189環(huán)指蛋白189抗體
xy-7613R    RNF144BE3泛素蛋白連接酶144B/環(huán)指蛋白144B抗體