Smad核轉(zhuǎn)錄共抑制因子抗體

英文名稱 SnoN
中文名稱 Smad核轉(zhuǎn)錄共抑制因子抗體
別    名 SKI like; Ski related oncogene; Ski related protein; SKIL; SnoA; SNO; SnoA; SnoI; SnoN; SKIL_HUMAN.
 
說 明 書 0.1ml  0.2ml  
研究領域 腫瘤  細胞生物  免疫學  染色質(zhì)和核信號  信號轉(zhuǎn)導  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 77kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SnoN
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
SnoN may have a regulatory role in cell division or differentiation in response to extracellular signals. SnoN acts as a positive mediator of TGF beta induced transcription and cell cycle arrest in lung epithelial cells. The ability of SnoN to repress the growth inhibitory function of the Smad proteins is required for their transforming activity.

Function:
May have regulatory role in cell division or differentiation in response to extracellular signals.

Subunit:
Interacts with SMAD2, SMAD3 and RNF111. Isoform 1 interacts with WWP1.xy-7103R    THAP1核凋亡因子THAP1抗體
xy-7105R    TIA1細胞毒顆粒相關蛋白TIA-1抗體
xy-7104R    THYN1胸腺細胞核蛋白1抗體
xy-7551R    TNFAIP3 interacting protein 3腫瘤壞死因子α誘導相互作用蛋白3抗體
xy-12097R    TRPV3辣椒素受體3抗體
xy-12105R    TEX261TEX261蛋白抗體
xy-2087R    TSHR促甲狀腺素受體抗體
xy-3457R    Phospho-TrkA(Tyr674 + Tyr675) + TrkB(Tyr706 + Tyr707)磷酸化酪氨酸激酶A抗體
xy-1444R    TLR3Toll樣受體3抗體
xy-1450R    TCRGT細胞受體γ抗體
xy-4514R    Transketolase (CT)轉(zhuǎn)酮醇酶(轉(zhuǎn)羥乙醛酶)抗體（C端）
xy-1215R    TPH色氨酸羥化酶抗體
xy-1214R    TRAIL腫瘤壞死因子相關凋亡誘導配體抗體
xy-0152R    Prealbumin轉(zhuǎn)甲狀腺素蛋白/前白蛋白抗體
xy-1151R    TRF1端粒體復制結合因子1抗體
xy-0193R    TrkA酪氨酸激酶A抗體
xy-1212R    TRAF1腫瘤壞死因子受體相關因子1抗體
xy-1213R    TRAF2 腫瘤壞死因子受體相關因子2抗體
xy-0157R    Tau protein微管相關蛋白抗體
xy-0822R    TARDBPTar DNA 結合蛋白43抗體
xy-1039R    Tenascin C細胞粘合素(固生蛋白)抗體
xy-0535R    TFF3三葉肽因子3抗體
xy-1144R    TFPI-2組織因子途徑抑制劑-2抗體
xy-0066R    TGF alpha轉(zhuǎn)移生長因子α抗體(TGFα)
xy-0103R    TGF Beta 1轉(zhuǎn)化生長因子β1抗體（TGFβ1）
xy-0100R    TGF beta 2 Propeptide轉(zhuǎn)移生長因子β2抗體（TGFβ2）
xy-0099R    TGF beta 3 propeptide轉(zhuǎn)移生長因子β3抗體（TGFβ3）
xy-0117R    TGF beta Receptor II轉(zhuǎn)移生長因子β受體2抗體（TGF-βRⅡ，TGFβRⅡ）
xy-0638R    TGF beta Receptor I轉(zhuǎn)移生長因子β受體1抗體