長鏈脂肪酸輔酶A連接酶抗體

英文名稱 SLC27A2
中文名稱 長鏈脂肪酸輔酶A連接酶抗體
別    名 ACSVL1; FACVL1; FATP 2; FATP2; Fatty acid coenzyme A ligase, very long chain 1; Fatty acid transport protein 2; hFACVL1; HsT17226; Long chain fatty acid CoA ligase; Solute carrier family 27 (fatty acid transporter), member 2; Solute carrier family 27 member 2; THCA CoA ligase; Very long chain acyl CoA synthetase; Very long chain fatty acid CoA ligase; Very long chain fatty acid coenzyme A ligase 1; VLACS; VLCS; S27A2_HUMAN.

說 明 書 0.1ml  0.2ml  
研究領域 腫瘤  免疫學  發(fā)育生物學  信號轉(zhuǎn)導  轉(zhuǎn)錄調(diào)節(jié)因子  轉(zhuǎn)運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 70kDa
細胞定位 細胞漿 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC27A2/ACSVL1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
SLC27A2 is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long chain fatty acids into fatty acyl-CoA esters, and thereby may play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. 

Function:
Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity).

Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Peroxisome membrane; Multi-pass membrane protein.xy-12446R    LPCAT2磷脂?；D(zhuǎn)移酶2抗體
xy-12438R    LRRFIP2LRRFIP2蛋白抗體
xy-12439R    LRRFIP1巨噬細胞調(diào)控相關蛋白LRRFIP1抗體
xy-0951R    LH beta促黃體生成素抗體
xy-5951R    LIMS1整合素和生長因子樣蛋白1抗體
xy-4771R    LLGL2相似腫瘤抑制基因HUGL抗體
xy-13687R    LAMTOR1LAMTOR1蛋白抗體
xy-13649R    LDB3LIM結構域結合蛋白3抗體
xy-13650R    LIMS2ILK結合蛋白LIMS2抗體
xy-13651R    LNK淋巴細胞特異性接頭蛋白抗體
xy-7349R    LILRB2細胞表面免疫球蛋白樣轉(zhuǎn)錄因子4抗體
xy-13652R    LY6G6F淋巴細胞抗原6重復位點蛋白G6F抗體
xy-13653R    Leupaxin樁蛋白抗體
xy-6055R    LRPAP1脂蛋白受體相關蛋白/低密度脂蛋白相關蛋白的相關蛋白1抗體
xy-6068R    LEPREL2皮屑樣蛋白2抗體
xy-1969R    LAMA3層粘蛋白α3抗體
xy-1970R    LAMP1溶酶體相關膜蛋白1抗體
xy-1971R    Lxn/Latexin羧肽酶抑制劑抗體
xy-1972R    LCAT卵磷酯膽固醇?；D(zhuǎn)移酶抗體
xy-1973R    LPL/PLASTIN2脂蛋白脂酶抗體
xy-0961R    Leptin receptor瘦素受體抗體
xy-2905R    LRP6低密度脂蛋白受體相關蛋白6抗體
xy-3253R    Phospho-LRP6 (Ser1490)磷酸化低密度脂蛋白受體相關蛋白6抗體
xy-3245R    Phospho-LATS1 (Thr1079)磷酸化腫瘤抑制基因LATS1抗體
xy-0683R    LRRK2富亮氨酸重復激酶2抗體
xy-0661R    LRP肺耐藥相關蛋白抗體
xy-9329R    LRCH3富含亮氨酸重復家庭蛋白3抗體
xy-9466R    LRRC10富含亮氨酸重復蛋白10抗體
xy-9328R    LRCH2富含亮氨酸重復家庭蛋白2抗體
xy-7615R    LRDD富含亮氨酸重復死亡結構域蛋白抗體
xy-0901R    LAMR1(CT)層粘連蛋白受體1抗體（C端）
xy-0900R    LAMR1層粘連蛋白受體1抗體（N端）
xy-9842R    phospho-LEF1(Ser42)磷酸化淋巴增強因子-1抗體
xy-11351R    LAP1層粘連相關多肽蛋白1抗體
xy-11175R    Lubricin淺表層粘膜蛋白多糖抗體