線粒體內(nèi)鈣結(jié)合天冬氨酸/谷氨酸載體蛋白抗體

英文名稱 SLC25A13
中文名稱 線粒體內(nèi)鈣結(jié)合天冬氨酸/谷氨酸載體蛋白抗體
別    名 ARALAR2; Calcium binding mitochondrial carrier protein Aralar2; Citrin; CTLN2; Ctrn; Mitochondrial aspartate glutamate carrier 2; RGD1565889; Solute carrier family 25 (citrin) member 13; Solute carrier family 25 member 13 (citrin); Solute carrier family 25 member 13; AI785475; CMC2_HUMAN.
 
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  結(jié)合蛋白  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 74kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 線粒體
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC25A13
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
SLC25A13 is a member of the mitochondrial carrier family. It contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. It catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in the SLC25A13 gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.

Function:
Catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. May have a function in the urea cycle. 

Subcellular Location:
Mitochondrion inner membrane; Multi-pass membrane protein. 

Tissue Specificity:
High levels in liver and low levels in kidney, pancreas, placenta, heart and brain. xy-5407R    phospho-LRP5(Thr1492)磷酸化低密度脂蛋白受體相關(guān)蛋白5抗體
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xy-12397R    MAML2主導(dǎo)控制樣蛋白2抗體
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xy-9291R    MUL1E3泛素連接酶MUL1抗體
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xy-8481R    MHC Class II組織相容性復(fù)合體蛋白2抗體