S腺苷L-同型半胱氨酸水解酶抗體

英文名稱 SAHH
中文名稱 S腺苷L-同型半胱氨酸水解酶抗體
別    名 Adenosylhomocysteinase; AdoHcyase; ahcY; S adenosyl L homocysteine hydrolase; S adenosylhomocysteine hydrolase; S-adenosyl-L-homocysteine hydrolase; SAHH; SAHH_HUMAN.
 
說 明 書 0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 48kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SAHH
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.

Function:
Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. 

Subunit:
Homotetramer.

Subcellular Location:
Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

DISEASE:
Defects in AHCY are the cause of hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) [MIM:613752]. A metabolic disorder characterized by hypermethioninemia associated with failure to thrive, mental and motor retardation, facial dysmorphism with abnormal hair and teeth, and myocardiopathy. 

Similarity:
Belongs to the adenosylhomocysteinase family.xy-4622R    Mycobacterium bovis牛結(jié)核桿菌菌體蛋白抗體
xy-6844R    MALT淋巴細(xì)胞成熟相關(guān)蛋白抗體
xy-6843R    MAGED1黑色素瘤相關(guān)抗原D1抗體
xy-6839R    MIER2中胚層誘導(dǎo)早期反應(yīng)蛋白2抗體
xy-7663R    MDMXMDM2樣P53蛋白結(jié)合抗體
xy-7616R    MCG10RNA相關(guān)結(jié)合蛋白MCG10抗體
xy-9624R    MRPS4線粒體核糖體蛋白S4抗體
xy-12099R    MUPP1緊密連接蛋白MUPP1抗體
xy-11217R    MTMR14肌管素相關(guān)蛋白14抗體
xy-11227R    Microcephalin 1/BRIT1小腦癥基因1/認(rèn)知相關(guān)蛋白抗體
xy-11234R    Miz1/ZNF60鋅指蛋白60抗體
xy-11264R    MYO6肌球蛋白6抗體
xy-9566R    Musclin肌肉素抗體
xy-12012R    MGLUR3代謝型谷氨酸受體-3抗體
xy-12013R    MGLUR2 + MGLUR3促代謝型谷氨酸受體2+3抗體
xy-12014R    MGLUR1 + MGLUR5促代謝型谷氨酸受體1+5抗體
xy-4899R    MICAMHC I類鏈相關(guān)蛋白A/組織相容性復(fù)合物MHCIa抗體
xy-9389R    MURF2肌肉特異性環(huán)指蛋白2抗體
xy-9390R    MURF3肌肉特異性環(huán)指蛋白3抗體
xy-7919R    phospho-MST1R(Tyr1353) 磷酸化原癌基因c-Met相關(guān)酪氨酸激酶抗體
xy-7920R    MAPK13絲裂原活化蛋白激酶13抗體
xy-12399R    Multicilin多纖毛素蛋白抗體
xy-7936R    MTMR8肌管素相關(guān)蛋白8抗體
xy-6412R    MRC2巨噬細(xì)胞甘露糖受體2抗體
xy-7896R    MNAT1細(xì)胞周期G1的相互作用蛋白抗體
xy-12398R    MAML3主導(dǎo)控制樣蛋白3抗體
xy-1689R    MEK3絲裂原活化蛋白激酶MKK3抗體
xy-2166R    MYSM1MYSM1抗體
xy-1569R    MCT1單羧酸轉(zhuǎn)運(yùn)蛋白-1抗體
xy-1847R    MAP1A微管相關(guān)蛋白1A抗體
xy-1849R    Midkine中期因子/肝素結(jié)合生長因子抗體
xy-1850R    Mineralocorticoid receptor鹽皮質(zhì)激素受體抗體
xy-1848R    alpha MSH促黑細(xì)胞激素α抗體