核突觸蛋白相互作用蛋白1抗體

英文名稱 Synphilin-1
中文名稱 核突觸蛋白相互作用蛋白1抗體
別    名 Synphilin-1; Synphilin1; Synphilin 1; Alpha-synuclein-interacting protein; Sncaip; Syph1, Syph 1,Syph-1; Alpha synuclein interacting protein; MGC39814; SNCAIP; SNCAP_HUMAN; Sph1; Synuclein alpha interacting protein (synphilin); SYPH 1.
  
說(shuō) 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 100kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Synphilin-1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of only two have been determined. [provided by RefSeq, Jul 2011].

Function:
Isoform 2 inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins. Isoform 2 inhibits autoubiquitination and proteasomal degradation of SIAH1, and thereby increases cellular levels of SIAH. Isoform 2 modulates SNCA monoubiquitination by SIAH1.xy-10305R    PIM1+PIM3絲氨酸/蘇氨酸激酶蛋白PIM1+PIM3抗體
xy-13659R    PACSIN3胞漿蛋白PACSIN3抗體
xy-13695R    PAG1跨膜接頭蛋白PAG抗體
xy-13696R    PARD6GPARD6G蛋白抗體
xy-13697R    PL6胎盤蛋白6抗體
xy-13675R    PIK3AP1磷酸肌醇3激酶接頭蛋白1抗體
xy-12676R    PRAM1PRAM1蛋白抗體
xy-10403R    Pan Cytokeratin/p-CK廣譜細(xì)胞角蛋白PCK抗體
xy-10157R    PDZ RHOGEF/GTRAP48Rho鳥(niǎo)甘酸轉(zhuǎn)運(yùn)蛋白抗體
xy-5538R    phospho-PIK3R1(Tyr368)磷酸化磷脂酰肌醇激酶抗體
xy-5552R    phospho-PARK2(Ser101)磷酸化帕金蛋白抗體
xy-5553R    phospho-PARK2(Ser378)磷酸化帕金蛋白抗體
xy-5554R    Phospho-PDGF Receptor beta (Tyr579)磷酸化血小板源性生長(zhǎng)因子受體B抗體
xy-5555R    Phospho-PDGF Receptor beta (Tyr716)磷酸化血小板源性生長(zhǎng)因子受體B抗體
xy-4153R    PAK6P21蛋白激活的蛋白激酶6抗體
xy-5556R    phospho-PAK6(Ser165)磷酸化P21蛋白激活的蛋白激酶6
xy-4154R    PTPRA酪氨酸磷酸酶α抗體
xy-4155R    PTPN7非受體型蛋白酪氨酸磷酸酶7抗體
xy-5557R    phospho-PTPN7 (Ser246)磷酸化非受體型蛋白酪氨酸磷酸酶7抗體
xy-5558R    phospho-PTPN7 (Ser93)磷酸化非受體型蛋白酪氨酸磷酸酶7抗體
xy-5559R    phospho-PKC delta (Ser645)磷酸化蛋白激酶C亞性D型抗體
xy-4156R    PKC mu蛋白激酶C mu型抗體
xy-1704R    PAI-1纖溶酶原激活物抑制因子抗體
xy-1551R    Pepsinogen II胃蛋白酶原C抗體
xy-5562R    phospho-PRKD1(Ser742)磷酸化蛋白激酶C mu型抗體
xy-1556R    Profilin 1前纖維蛋白1抗體
xy-2006R    PCNA-Proliferation Marker增殖細(xì)胞核抗原抗體
xy-5540R    phospho-FAK(Tyr925)磷酸化粘著斑激酶抗體
xy-5541R    phospho-PTK2(Tyr576+Tyr577)磷酸化粘著斑激酶抗體
xy-5542R    phospho-PAK1(Thr212)磷酸化p21激活激酶1抗體
xy-5543R    Phospho-PDPK1(Tyr9)磷酸化3磷酸肌醇依賴性蛋白激酶1抗體
xy-5544R    Phospho-PDPK1(Ser396)磷酸化3磷酸肌醇依賴性蛋白激酶1抗體
xy-5545R    Phospho-PDPK1(Ser410)磷酸化3磷酸肌醇依賴性蛋白激酶1抗體