平滑肌肌球蛋白重鏈抗體

英文名稱 SMMHC
中文名稱 平滑肌肌球蛋白重鏈抗體
別    名 Myosin, smooth muscle, heavy chain; Myosin Smooth Muscle; AAT 4; AAT4; DKFZp686D10126; DKFZp686D19237; FAA 4; FAA4; FLJ35232; KIAA0866; MGC126726; MGC32963; MYH 11; MYH11 protein; Myosin 11; Myosin heavy chain 11 smooth muscle; Myosin heavy chain smooth muscle isoform; Myosin heavy polypeptide 11 smooth muscle; Myosin11; SMHC; Smooth muscle myosin heavy chain 11; Smooth muscle myosin heavy chain isoform SM1; MYH11_HUMAN.
  
說(shuō) 明 書(shū) 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  心血管  免疫學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Cow, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 227kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SMHC
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16[inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified. 
MYH11 is a smooth muscle myosin belonging to the myosin heavy chain family. It is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP.xy-5597R    phospho-P53(Ser376)磷酸化腫瘤抑制基因P53抗體
xy-6061R    PIGR多聚免疫球蛋白受體抗體
xy-11135R    PCDHB16原鈣粘蛋白16抗體
xy-6062R    PRDM2鋅指蛋白R(shí)IZ1抗體
xy-6063R    PRMT6組蛋白精氨酸甲基轉(zhuǎn)移酶6抗體
xy-6064R    PRSS8絲氨酸蛋白酶8抗體
xy-1652R    phospho-PAK1/2/3(Thr423)磷酸化p21激活激酶1/2/3抗體
xy-6051R    Prostaglandin dehydrogenase 1前列腺素脫氫酶1抗體
xy-2505R    phospho-PRKCZ(Thr500)磷酸化蛋白激酶C(T500)抗體
xy-1650R    phospho-P53(Ser392)磷酸化腫瘤抑制基因P53抗體
xy-1653R    phospho-PAK1 (Ser144)磷酸化p21激活激酶1抗體
xy-1654R    phospho-PAK2 (Ser141)磷酸化p21激活激酶2抗體
xy-1655R    phospho-PAK3 (Ser139)磷酸化p21激活激酶3抗體
xy-1651R    phospho-PAK1+PAK2+PAK3 (Ser141)磷酸化p21激活激酶1/2/3抗體
xy-1656R    phospho-P70 S6 Kinase beta (Thr228)磷酸化核糖體S6蛋白激酶抗體
xy-2638R    PROK1/PRK1/EG-VEGF內(nèi)分泌腺衍生血管內(nèi)皮生長(zhǎng)因子抗體
xy-2469R    PERK蛋白激酶樣內(nèi)質(zhì)網(wǎng)激酶抗體
xy-2899R    PMSA前列腺特異膜抗原抗體
xy-0128R    PI3 kinase p85 alpha subunit磷脂酰肌醇激酶抗體
xy-0234R    PLGF胎盤(pán)生長(zhǎng)因子抗體
xy-0520R    PKA alpha + beta蛋白激酶A抗體
xy-0267R    PKC beta 1 + 2蛋白激酶C beta 1/2抗體
xy-0281R    PLGF胎盤(pán)生長(zhǎng)因子抗體
xy-0280R    PLGF胎盤(pán)生長(zhǎng)因子抗體
xy-0235R    PMP22外周髓鞘蛋白-22抗體
xy-1048R    Podoplanin平足蛋白抗體(淋巴管內(nèi)皮細(xì)胞蛋白)
xy-0133M    PP-1B蛋白磷酸酯酶-1B抗體
xy-0029R    PP2A alpha + beta蛋白質(zhì)磷酸酶-2A抗體
xy-0490R    PPP4C磷酸酯酶-2Ac抗體