電壓開啟的鈉離子通道SCN9A抗體

英文名稱 NAV1.7
中文名稱 電壓開啟的鈉離子通道SCN9A抗體
別    名 SCN9A; Sodium channel protein type 9 subunit alpha; ETHA; hNE Na; hNENa; NE NA; NENA; NE-NA; Neuroendocrine sodium channel; Peripheral sodium channel 1; PN1; SCN9A; Sodium channel protein type 9 subunit alpha; Sodium channel protein type IX subunit alpha; Sodium channel voltage gated type IX alpha; Sodium channel voltage gated type IX alpha polypeptide; Sodium channel voltage gated type IX alpha subunit; Voltage gated sodium channel alpha subunit Nav1.7; Voltage gated sodium channel subunit alpha Nav1; FEB3B; SCN9A_HUMAN.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Cow, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 219kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SCN9A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. [provided by RefSeq, Aug 2009]

Function:
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na(+) channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain.

Subunit:
The sodium channel consists of a large polypeptide and 2-3 smaller ones. This sequence represents a large polypeptide. Interacts with NEDD4 and NEDD4L.xy-11136R    PCDHB2原鈣粘蛋白β2抗體
xy-11138R    PCDHB4原鈣粘蛋白β4抗體
xy-11143R    PCDHGA10原鈣粘蛋白γ10抗體
xy-11144R    PCDHGA4原鈣粘蛋白γA4抗體
xy-11145R    PCDHGA2原鈣粘蛋白γA2抗體
xy-11147R    PCDHGA5原鈣粘蛋白γA5抗體
xy-11148R    PCDHGA7原鈣粘蛋白γA7抗體
xy-11149R    PCDHGA8原鈣粘蛋白γA8抗體
xy-11150R    PCDHGA9原鈣粘蛋白γA9抗體
xy-11151R    PCDHGA11原鈣粘蛋白γA11抗體
xy-11152R    PCDHGA12原鈣粘蛋白γA12抗體
xy-11153R    PCDHB12原鈣粘蛋白β12抗體
xy-11154R    PCDHB3原鈣粘蛋白β3抗體
xy-11155R    PCDHGB1原鈣粘蛋白γB1抗體
xy-11156R    PCDHGB2原鈣粘蛋白γB2抗體
xy-11157R    PCDHGB4原鈣粘蛋白γB4抗體
xy-11158R    PCDHGB6原鈣粘蛋白γB6抗體
xy-11159R    PCDHGC3原鈣粘蛋白γC3抗體
xy-11160R    PCDHGC4原鈣粘蛋白γC4抗體
xy-11327R    PTP zeta磷酸蛋白聚糖PTPRZ抗體
xy-11328R    PTPN5/STEP神經(jīng)特異蛋白酪氨酸磷酸酶N5抗體
xy-8688R    POD1足細(xì)胞表達(dá)蛋白/轉(zhuǎn)錄因子21抗體
xy-0183R    progesterone receptor孕激素受體抗體
xy-11354R    Piccolo神經(jīng)細(xì)胞突觸蛋白PCLO抗體
xy-6456R    PEN2 早老素γ分泌酶2抗體
xy-8337R    PANK1泛酸激酶1抗體
xy-8338R    PANK2泛酸激酶2抗體
xy-8339R    PANK3泛酸激酶3抗體
xy-8325R    PA26p53調(diào)控PA26核蛋白抗體
xy-8322R    Proteasome 19S S5A26S蛋白酶調(diào)節(jié)亞型S5a抗體
xy-8328R    PP4R3B絲氨酸/蘇氨酸蛋白磷酸酶3B抗體
xy-9547R    PGGT1A蛋白香葉烯基轉(zhuǎn)移酶1α抗體