核突觸蛋白-α抗體（N端）

英文名稱 alpha-Synuclein
中文名稱 核突觸蛋白-α抗體（N端）
別    名 Alpha synuclein; Alpha-Synuclein; Alpha-synuclein, isoform NACP140; alpha SYN; MGC105443; MGC110988; MGC127560; MGC64356; NACP; Non A beta component of AD amyloid; Non A4 component of amyloid precursor; Non-A-beta component of alzheimers disease amyloid , precursor of; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; PARK 1; PARK 4; PARK1; PARK4; Parkinson disease (autosomal dominant, Lewy body) 4; Parkinson disease familial 1; PD 1; PD1; Syn; SNCA; Snca synuclein, alpha (non A4 component of amyloid precursor); SYUA_HUMAN; Synuclein alpha; Synuclein, alpha (non A4 component of amyloid precursor);
 
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  細(xì)胞凋亡  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Pig, Cow, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human alpha-Synuclein N-terminus
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Alpha Synuclein is implicated in the regulation of dopamine release and transport. It is a soluble protein, expressed principally in the brain but also expressed in low concentrations in all tissues examined (except liver). In the nervous system, alpha Synuclein is primarily located at presynaptic terminals and is found membrane bound in dopaminergic neurons. It can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies), including Parkinson's Disease. Alpha Synuclein induces fibrillization of microtubule associated protein tau and reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase 3 activation. Alpha synuclein is a protein phosphorylated predominantly on serine residues.xy-7006R    RASD2腫瘤血管內(nèi)皮標(biāo)記蛋白2抗體
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xy-5941R    RRAS2畸胎瘤癌基因RAS相關(guān)病毒抗體
xy-5954R    RASA3Ras-GTP酶激活蛋白3抗體
xy-11798R    Reticulon 1神經(jīng)內(nèi)分泌特異性蛋白抗體
xy-6214R    RDH11視黃醇脫氫酶11/丙型肝炎病毒核心蛋白抗體
xy-6216R    ROR beta維甲酸相關(guān)孤兒受體β抗體
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xy-6180R    Rab3A+Rab3B+Rab3C+Rab3Dras癌基因家族Rab3A--Rab3D抗體
xy-6156R    RASGEF1A鳥嘌呤核苷酸交換因子rasgef1a抗體
xy-6514R    RLLM1胰腺癌轉(zhuǎn)移相關(guān)蛋白R(shí)LLM1抗體
xy-6511R    RNF45環(huán)指蛋白45/自分泌運(yùn)動(dòng)因子受體抗體
xy-6215R    ROR alpha維甲酸相關(guān)孤兒受體α抗體
xy-6217R    RORG維甲酸相關(guān)孤兒受體γ抗體
xy-6157R    RAB4癌基因RAS相關(guān)蛋白R(shí)ab4A抗體
xy-2960R    ROM-KATP調(diào)節(jié)鉀離子通道ROM K抗體
xy-3868R    Rab24ras基因相關(guān)蛋白R(shí)ab24抗體
xy-11941R    RDH10視黃醇脫氫酶10抗體
xy-3832R    RHEBRas蛋白腦組織同源類似物RHEB蛋白抗體
xy-2330R    RAP2B原癌基因相關(guān)蛋白R(shí)AP2B抗體
xy-6016R    RBBP5視網(wǎng)膜母細(xì)胞瘤結(jié)合蛋白5抗體
xy-10173R    ROCK2Rho相關(guān)蛋白激酶2抗體
xy-7133R    RRM2核糖核苷酸還原酶亞基R2抗體
xy-4860R    Runx3Runx3抗體
xy-10097R    RRAGCRAS相關(guān)GTP結(jié)合蛋白C抗體
xy-3675R    R-cadherinR-鈣粘附分子抗體
xy-6168R    RAB8Bras癌基因家族RAB8B抗體
xy-6169R    RALBRas樣蛋白B抗體
xy-6123R    Rb2 p130視網(wǎng)膜母細(xì)胞瘤相關(guān)蛋白p130抗體