陰離子轉運蛋白-1抗體

英文名稱 SLC22A6
中文名稱 陰離子轉運蛋白-1抗體
別    名 Organic anion transporter 1; OAT1; OAT-1; solute carrier family 21 (organic anion transporter), member 6; FLJ55736; HOAT1; MGC124962; MGC45260; mOat1; NKT; Oat; Orctl1; PAHT; ROAT1; SLC22A6; SO1A1_RAT.
 
說 明 書 0.1ml  0.2ml  
研究領域 轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 61kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse OAT-1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Recent advances in molecular biology have identified three organic anion transporter families: the organic anion transporter (OAT) family encoded by SLC22A, the organic anion transporting peptide (OATP) family encoded by SLC21A (SLCO), and the multidrug resistance-associated protein (MRP) family encoded by ABCC. These families play critical roles in the transepithelial transport of organic anions in the kidneys as well as in other tissues such as the liver and brain. Among these families, the OAT family plays the central role in renal organic anion transport. Knowledge of these three families at the molecular level, such as substrate selectivity, tissue distribution, and gene localization, is rapidly increasing.

Function:
Mediates the Na(+)-independent transport of organic anions such as taurocholate, prostaglandin E2 (PGE2), dehydroepiandrosterone sulfate (DHEAS), 17-beta-glucuronosyl estradiol, estrone-3-sulfate, sulfobromophthalein (BSP), ouabain and gadoxetate.xy-8530R    SDHC琥珀酸細胞色素亞基B560抗體
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xy-12046R    5HT1D Receptor5-羥色胺受體1D抗體
xy-12047R    5HT1E Receptor5-羥色胺受體1E抗體
xy-12048R    5HT1F Receptor5-羥色胺受體1F抗體
xy-12049R    5HT2A Receptor5-羥色胺受體2A抗體
xy-12050R    5HT2B Receptor5-羥色胺受體2B抗體
xy-12051R    5HT3A Receptor5-羥色胺受體3A抗體
xy-12052R    5HT3D + 5HT3E Receptor5-羥色胺受體3D+3E抗體
xy-12053R    5HT3D Receptor5-羥色胺受體3D抗體
xy-12054R    5HT4 Receptor5-羥色胺受體4抗體
xy-12055R    5HT5A receptor5-羥色胺受體5A抗體
xy-12056R    5HT7 Receptor5-羥色胺受體7抗體
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xy-7873R    S100 alpha 2S100A2抗體
xy-7901R    SPDYA細胞周期G2/M期快速誘導蛋白SPDYA抗體
xy-12058R    5HT6 Receptor5-羥色胺受體6抗體
xy-6402R    SMARCA2ATP依賴解旋酶SMARCA2抗體
xy-8389R    SKP1S期激酶相關蛋白1抗體
xy-8390R    SHFM3SHFM3蛋白抗體
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xy-7878R    STAM信號轉導銜接蛋白1抗體
xy-5332R    phospho-SLK (Tyr530)磷酸化酪氨酸蛋白激酶Fyn/同步原癌基因抗體
xy-9027R    SPTLC2絲氨酸棕櫚酰轉移酶2抗體