鋅指蛋白592抗體

英文名稱 ZNF592
中文名稱 鋅指蛋白592抗體
別    名 8430405N24; A730014M16Rik; CAMOS; KIAA0211; MGC138437; MGC138439; mKIAA0211; SCAR5; Zfp592; Zinc finger protein 592; ZNF 592; ZNF592.
  
說 明 書 0.2ml  
研究領(lǐng)域 神經(jīng)生物學  轉(zhuǎn)錄調(diào)節(jié)因子  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 137kDa
細胞定位 細胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNF592
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene is thought to play a role in a complex developmental pathway and the regulation of genes involved in cerebellar development. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia. [provided by RefSeq, Jan 2011]

Function:
May be involved in transcriptional regulation.

Subcellular Location:
Nuclear.

Tissue Specificity:
Widely expressed, with highest levels in skeletal muscle. Expressed throughout the central nervous system, including in the cerebellum and cerebellar vermis, with higher expression in the substantia nigra. Widely expressed in fetal tissues.

DISEASE:
The disease is caused by mutations affecting the gene represented in this entry. 
Disease description:Spinocerebellar ataxia defines a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCAR5 patients show developmental delay, psychomotor retardation, proportionate short stature, cerebellar spastic ataxia, microcephaly, optic atrophy, speech defect, abnormal osmiophilic pattern of skin vessels and cerebellar atrophy. xy-8717R    SLC30A3溶質(zhì)載體鋅轉(zhuǎn)運3抗體
xy-8324R    SERPINB13絲氨酸蛋白酶抑制劑13抗體
xy-8330R    STK25絲氨酸/蘇氨酸激酶25抗體
xy-7879R    SUPT16H染色體特異性轉(zhuǎn)錄延伸因子抗體
xy-11863R    KIAA1598閱讀障礙相關(guān)蛋白Shootin抗體
xy-7732R    Separase外紡錘體極樣蛋白1抗體
xy-3667R    SLC44A1溶質(zhì)轉(zhuǎn)運蛋白家族44成員1抗體
xy-10085R    SLC7A9離子轉(zhuǎn)運相關(guān)蛋白SLC7A9抗體
xy-8610R    SLC20A2溶質(zhì)載體蛋白家族20成員2抗體
xy-10098R    S100A6S100鈣結(jié)合蛋白A6抗體
xy-12364R    SCXA堿性螺旋-環(huán)-螺旋轉(zhuǎn)錄因子SCXA抗體
xy-12346R    Stabilin 2清道夫受體STAB2抗體
xy-12351R    STRA6維甲酸誘導蛋白6抗體
xy-10200R    Sclerostin骨形態(tài)發(fā)生抑制蛋白SOST抗體
xy-10367R    Sarcomeric Alpha Actininα橫紋肌輔肌動蛋白/α-SCA抗體
xy-12317R    SCUBE3新型分泌細胞表面蛋白/成骨細胞相關(guān)蛋白SCUBE3抗體
xy-12318R    SCUBE2內(nèi)皮分泌蛋白SCUBE2抗體
xy-7120R    Sulfite oxidase亞硫酸鹽氧化酶抗體
xy-8877R    Somatostatin生長抑素抗體
xy-10315R    phospho-Syntaxin 1a(Ser188)磷酸化突觸融合蛋白1抗體
xy-3787R    SCD1固醇酰輔酶A脫氫酶1抗體
xy-6015R    SNF2L解旋酶SNF2L抗體
xy-3829R    Sorbitol Dehydrogenase山梨醇脫氫酶抗體
xy-2381R    Signal recognition particle信號識別顆?？贵w
xy-6158R    SH2D3ASH2結(jié)構(gòu)域蛋白3A抗體
xy-2943R    SEMA6D軸突導向因子SEMA6D抗體
xy-6531R    SKALP彈性蛋白酶抑制劑抗體
xy-2971R    STK39絲氨酸/蘇氨酸蛋白激酶39抗體
xy-5621R    phospho-STAT5a(Tyr694)磷酸化信號轉(zhuǎn)導和轉(zhuǎn)錄激活因子5a抗體
xy-5633R    phospho-SYT1(Thr202)磷酸化突觸結(jié)合蛋白1抗體
xy-5619R    phospho-STAT5a(Ser726)磷酸化信號轉(zhuǎn)導和轉(zhuǎn)錄激活因子5a抗體
xy-5620R    phospho-STAT5a(Ser780)磷酸化信號轉(zhuǎn)導和轉(zhuǎn)錄激活因子5a抗體