鋅指蛋白樣1抗體

英文名稱 ZFPL1
中文名稱 鋅指蛋白樣1抗體
別    名 D11S750; MCG4; MGC 4; ZFPL 1; Zinc finger protein like 1; Zinc finger protein MCG4; zinc-finger protein in MEN1 region.
  
說(shuō) 明 書(shū) 0.2ml  
研究領(lǐng)域 細(xì)胞生物  鋅指蛋白  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, Cat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZFPL1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Zinc finger protein-like 1 is a 310 amino acid single-pass membrane protein with two zinc fingers at the N-terminus, the second of which is likely a RING domain. The RING domain, which is a 40-60 amino acid, cysteine-rich domain that binds two atoms of zinc, plays a key role in the ubiquitination pathway. The presence of zinc finger-like and leucine zipper-like domains in ZFPL1 suggests a role in DNA binding and transcriptional regulation. ZFP1 is widely expressed in the golgi apparatus and is involved in maintaining golgi structure and regulating the rate of cargo transport.

Function:
Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis-Golgi, possibly via its interaction with GOLGA2/GM130.xy-11366R    SV2C突觸泡蛋白2C抗體
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xy-11478R    SEMA4F跨膜蛋白SEMA4F抗體
xy-11479R    SEMA4G跨膜蛋白SEMA4G抗體
xy-11480R    Semaphorin 3E軸突導(dǎo)向因子SEMA3E抗體
xy-8464R    SENP5泛素相關(guān)修飾蛋白特異性蛋白酶5抗體
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