鋅指RNA結(jié)合蛋白抗體

英文名稱 ZFR
中文名稱 鋅指RNA結(jié)合蛋白抗體
別    名 FLJ41312; hZFR; M phase phosphoprotein homolog; M-phase phosphoprotein homolog; zfr;
說 明 書 0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  結(jié)合蛋白  鋅指蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Cat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 117kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZFR
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the
PubMed PubMed
產(chǎn)品介紹 background:
ZFR is 1,074 amino acid RNA-binding protein. In human, ZFR is expressed in lung, liver, lymphocytes, heart, pancreas, kidney and placenta, and regulates postimplantation and gastrulation stages of development. Murine ZFR is observed in testis, ovary and brain. With elevated levels of expression during meiosis, ZFR associates with chromosome foci in meiotic cells. ZFR contains 1 DZF domain and localizes in the somatodendritic compartment of hippocampal neurons and colocalizes with STAU2 in cytosolic RNA granules. Knockout of ZFR in mouse embryo prevents the development of some embryonic structures leads to an increase in programmed cell death with a decrease in mitotic index.

Function:
Involved in postimplantation and gastrulation stages of development. Involved in the nucleocytoplasmic shuttling of STAU2. Binds to DNA and RNA.

Subcellular Location:
Nucleus. Cytoplasm. Cytoplasmic granule. Chromosome. Associated with chromosome foci in meiotic cells. Localizes in somatodendritic compartment of primary hippocampal neurons. Colocalizes with STAU2 in several cytosolic RNA granules.

Tissue Specificity:
Expressed in lung, liver, lymphocytes, heart, pancreas, placenta, brain and kidney.xy-5703R    phospho-STAT5b(Ser731) 磷酸化信號轉(zhuǎn)導(dǎo)和轉(zhuǎn)錄激活因子5b抗體
xy-3858R    SH2D2A血管內(nèi)皮生長因子受體相關(guān)蛋白抗體
xy-4031R    SLC9A9鈉氫通道蛋白9家族A9抗體
xy-4035R    SENP3類泛素蛋白3抗體
xy-2743R    SLIT2/Slil3神經(jīng)遷移蛋白Slit2/3抗體
xy-2801R    Smoothened跨膜蛋白Smoothened抗體
xy-2805R    Stanniocalcin 1斯鈣素抗體
xy-6399R    SIPA1信號誘導(dǎo)增殖相關(guān)蛋白1抗體
xy-6899R    STK40絲氨酸/蘇氨酸蛋白激酶40抗體
xy-3753R    SCG10神經(jīng)生長相關(guān)蛋白SCG10抗體
xy-3759R    S100A4S100A4抗體
xy-3919R    STARD5促黃體激素誘導(dǎo)蛋白5抗體
xy-3752R    Sca1T淋巴細(xì)胞激活蛋白抗體
xy-3388R    Phospho-RPS6 (Ser235+Ser236)磷酸化S6核糖體蛋白抗體
xy-3392R    Phospho-MEK4 (Ser257)磷酸化絲裂原活化蛋白激酶激酶4抗體
xy-3693R    Phospho-MEK4 (Thr261)磷酸化絲裂原活化蛋白激酶激酶4抗體
xy-3394R    Phospho-MEK4 (Ser257 + Thr261)磷酸化絲裂原活化蛋白激酶激酶4抗體
xy-4904R    SGK1糖皮質(zhì)激素調(diào)節(jié)激酶1抗體
xy-3340R    Phospho-PLC beta3 (Ser537)磷酸化磷酯酶Cβ3抗體
xy-3407R    Phospho-SMC1(Ser957)磷酸化染色體結(jié)構(gòu)維持蛋白質(zhì)１抗體
xy-0478R    SLC6A19鉀依賴鈉鈣交換蛋白6抗體
xy-9596R    SPAG17精子相關(guān)抗原17抗體
xy-1729R    phospho-Syndecan 4(Ser179)磷酸化多配體聚糖4(Ser179)抗體
xy-4938R    SDF1基質(zhì)細(xì)胞衍生因子1抗體
xy-4944R    SETBP1SET結(jié)合蛋白1抗體
xy-1368R    SSTR3生長抑素受體3抗體
xy-1382R    SNAI2鋅指轉(zhuǎn)錄因子Slug抗體
xy-7675R    SUZ12胚胎干細(xì)胞抑制蛋白Suz12抗體
xy-3501R    Synapsin 1神經(jīng)突觸素1抗體
xy-3289R    phospho-SYN1(Ser9)磷酸化神經(jīng)突觸素1抗體
xy-3290R    phospho-SYN1(Ser553)磷酸化神經(jīng)突觸素1抗體
xy-3519R    SLK酪氨酸蛋白激酶Fyn（同步原癌基因）抗體