原癌基因Yes相關(guān)蛋白1抗體

英文名稱 YAP1
中文名稱 原癌基因Yes相關(guān)蛋白1抗體
別    名 65 kDa Yes associated protein; YAp 1; YAP 65; YAP; YAP2; YAP65; Yes associated protein 1 65kDa; Yes associated protein 1; Yes associated protein 2; YKI.
    
說(shuō) 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human YAP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
YAP1 (also known as Yes associated protein 1) was originally identified as a transcription factor that binds to the SH3 domain of the YES kinase (a Src protein kinase). More recently it has been identified as a candidate oncogene that promotes tumorigenesis in many different types of cancer.

Subunit:
Binds to the SH3 domain of the YES kinase. Binds to WBP1 and WBP2. Binds, in vitro, through the WW1 domain, to neural isoforms of ENAH that contain the PPSY motif (By similarity). The phosphorylated form interacts with YWHAB. Interacts (via WW domains) with LATS1 (via PPxY motif 2). Interacts with LATS2. Isoform 2 and isoform 3 interact (via WW domain 1) with isoform 3 of ERBB4 (via PPxY motif 2). Interacts with TEAD1, TEAD2, TEAD3 and TEAD4. Interacts with TP73. Interacts with RUNX1. Interacts with HCK.

Subcellular Location:
Cytoplasm. Nucleus.xy-2647R    LAIR-1白細(xì)胞相關(guān)免疫球蛋白樣受體1抗體
xy-2650R    Langerin/CD207白細(xì)胞分化抗原CD207抗體
xy-2655R    LTB4-R2白三烯B4受體2抗體
xy-2648R    LAIR-2白細(xì)胞相關(guān)免疫球蛋白樣受體2抗體
xy-6069R    LLGL1相似腫瘤抑制基因HUGL抗體
xy-6319R    IL-1 Beta白介素1β抗體
xy-0814R    Beta-lactoglobulinβ-乳球蛋白抗體
xy-12150R    LPPR1脂質(zhì)磷酸磷酸酶相關(guān)蛋白1/可塑性相關(guān)基因3抗體
xy-12141R    LRFN1神經(jīng)突觸粘附樣分子1抗體
xy-9327R    LRCH1富含亮氨酸重復(fù)家庭蛋白1抗體
xy-9330R    LRCH4富含亮氨酸重復(fù)家庭蛋白4抗體
xy-0109R    Leptin receptor(long)瘦素受體抗體（長(zhǎng)）
xy-1058R    LIF白血病抑制因子抗體
xy-1177R    Lingo-1Nogo受體反應(yīng)蛋白抗體
xy-0738R    Livin凋亡抑制蛋白抗體
xy-0821R    laminin層粘連蛋白抗體
xy-0759R    Lpin1 proteinLpin1 抗體
xy-0760R    Lpin1 proteinLpin1 抗體
xy-0816R    Lysozyme溶菌酶抗體
xy-0484R    Iumbrokinase蚓激酶抗體
xy-0409R    Leptin瘦素抗體
xy-0410R    Leptin receptor瘦素受體抗體
xy-0109M    Leptin receptor(long)瘦素受體抗體（長(zhǎng)）
xy-9708R    LCE1A晚期包膜蛋白1抗體
xy-6862R    LANPL富含亮氨酸樣酸性核蛋白抗體
xy-9709R    LCE2B晚期包膜蛋白2B抗體
xy-9711R    LIPK脂肪酶家庭成員K抗體
xy-1902R    Stathmin白血病相關(guān)蛋白18/癌蛋白18抗體
xy-2035R    LIS1無(wú)腦回的致病基因LIS1抗體
xy-2556R    LAMP3溶酶體相關(guān)膜蛋白3抗體