軟骨細胞蛋白39抗體

英文名稱 CHI3L2
中文名稱 軟骨細胞蛋白39抗體
別    名 CH3L2_HUMAN; CHI3L2; Chitinase 3 like 2; Chitinase-3-like protein 2; Chondrocyte protein 39; OTTHUMP00000014028; YKL 39; YKL-39; YKL39.
規(guī)格價格 0.1ml/900元 購買    0.2ml/1480元 購買    
說 明 書 0.1ml  0.2ml  

抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
細胞定位 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human YKL39/CHI3L2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4
PubMed PubMed
產品介紹 background:
YKL-39 is a 390 amino acid cartilage protein that belongs to the chitinase family of chitin-fragmenting hydrolases. Highly expressed in chondrocytes (cartilage cells) and synoviocytes (fibroblastic cells that line joint cavities), YKL-39 binds glycan structures with high affinity. Although related to bacterial chitinases, YKL-39 lacks the characteristic glutamate active site and, thus, does not have enzymatic chitinase activity. Patients affected with rheumatoid arthritis (RA) have autoimmunity against YKL-39, suggesting that YKL-39 is involved in osteoarthritic and/or rheumatoid joint disease. Additionally, YKL-39 is upregulated in early degenerative cartilage diseases (such as RA) and may be a marker of chondrocyte activation in these autoimmune conditions.

Function:
May bind glycan structure with high affinity, but not heparin. Has no chitotriosidase activity.

Subcellular Location:
Secreted.xy-11881R    Lunatic Fringe信號轉導分子SCDO3抗體
xy-10030R    LEO1RNA聚合酶相關蛋白LEO1抗體
xy-6946R    LCMV淋巴細胞性脈絡叢腦膜炎病毒蛋白抗體
xy-11731R    LC3A/B自噬微管相關蛋白輕鏈3A/3B抗體
xy-10369R    Gonadoliberin-1黃體激素釋放激素/促性腺激素釋放激素抗體
xy-12311R    LRRC23LRRC23蛋白抗體
xy-12312R    LRRC39LRRC39蛋白抗體
xy-8878R    LC3自噬微管相關蛋白輕鏈3抗體
xy-12342R    L3MBTL3L3MBTL3蛋白抗體
xy-12339R    LRRC25富含亮氨酸重復蛋白25抗體
xy-2631R    IL-31RA/CRL3白介素31受體a抗體
xy-9387R    LRSAM1LRSAM1蛋白抗體
xy-7336R    Limd1LIM結構域蛋白1抗體
xy-2338R    Lactic acid bacterial protein surface乳酸菌菌體表面蛋白抗體
xy-4629R    Layilin透明質酸受體抗體
xy-3908R    LTA4H白三烯A4水解酶抗體
xy-2342R    LXR alpha肝臟X受體抗體
xy-6542R    LAPTM4B溶酶體蛋白跨膜β4抗體
xy-6545R    LRRN5富含亮氨酸重復神經元5抗體
xy-6546R    Lipophilin B親脂性蛋白B抗體
xy-6543R    LDOC1癌癥亮氨酸拉鏈下調因子1抗體
xy-6544R    LOXL2賴氨酰氧化酶相關蛋白2抗體
xy-5890R    Lumican基膜聚糖蛋白抗體
xy-10499R    Listeriolysin李斯特菌溶胞素抗體
xy-6249R    LCMT1亮氨酸羧基甲基轉移酶1抗體
xy-5937R    LETMD1宮頸癌原癌基因2抗體
xy-5790R    LOXL4賴氨酰氧化酶樣蛋白4抗體
xy-5810R    Lactoferrin乳鐵蛋白抗體
xy-7503R    Laminin 1+2層粘連蛋白1+2抗體
xy-6815R    LRRC15富含亮氨酸重復蛋白15抗體
xy-11530R    LAR受體蛋白酪氨酸磷酸酶F抗體
xy-13777R    Phospho-5-Lipoxygenase(Ser524)磷酸化5-脂氧合酶抗體