磷酸肌醇相互作用蛋白2抗體

英文名稱 WIPI2/Atg21
中文名稱 磷酸肌醇相互作用蛋白2抗體
別    名 ATG18B; Atg21; CGI 50; DKFZp434J154; DKFZp686P02188; FLJ12979; FLJ14217; FLJ42984; WD repeat domain phosphoinositide-interacting protein 2; WD repeat domain, phosphoinositide interacting 2; WD40 repeat protein interacting with phosphoinositides 2; WIPI 2; WIPI-2; WIPI2; WIPI2_HUMAN; WIPI49 like protein 2; WIPI49-like protein 2.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  細(xì)胞自噬  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 49kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human WIPI2/Atg21
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008]

Function:
Probable early component of the autophagy machinery being involved in formation of preautophagosomal structures and their maturation into mature phagosomes in response to PtdIns3P. May bind PtdIns3P.

Subunit:
Interacts with TECPR1.

Subcellular Location:
Preautophagosomal structure membrane. Enriched at preautophagosomal structure membranes in response to ptdIns3P.xy-6704R    NEDD5神經(jīng)前體細(xì)胞表達(dá)發(fā)育下調(diào)蛋白5抗體
xy-6711R    Netrin 4軸突生長誘向因子4抗體
xy-11594R    Nicalinγ-分泌酶組件蛋白NCLN抗體
xy-11572R    NR2E3核受體蛋白NR2E3抗體
xy-7815R    NEK8絲氨酸/蘇氨酸蛋白激酶NEK8抗體
xy-7819R    NUP37核孔蛋白Nup37抗體
xy-7816R    NSP5核結(jié)構(gòu)蛋白5抗體
xy-7817R    NUBP1核苷酸結(jié)合蛋白1抗體
xy-7818R    NUBP2核苷酸結(jié)合蛋白2抗體
xy-7757R    NAT10乙?；D(zhuǎn)移酶10抗體
xy-7758R    NEK7絲氨酸/蘇氨酸蛋白激酶Nek7抗體
xy-4142R    NPTX1神經(jīng)細(xì)胞正五聚體1抗體
xy-5097R    NNT煙酰胺核苷酸轉(zhuǎn)氫酶抗體
xy-2348R    Natriuretic Peptide Receptor B利鈉肽受體B抗體
xy-2333R    NPRC利鈉肽受體C抗體
xy-5381R    Phospho-NMDAR2B (Tyr1336)磷酸化谷氨酸受體2B抗體
xy-5380R    Phospho-NMDAR2B (Tyr1252)磷酸化谷氨酸受體2B抗體
xy-3889R    NOX2NADPH氧化酶2抗體
xy-3891R    NOXA2NADPH氧化酶活化蛋白1抗體
xy-5660R    phospho-NFKB p65(Ser529)磷酸化細(xì)胞核因子抗體
xy-5661R    phospho-NFKB p65(Thr435)磷酸化細(xì)胞核因子抗體
xy-5662R    phospho-NFKB p65(Thr254)磷酸化細(xì)胞核因子抗體
xy-5663R    phospho-NFKB p65(Thr505)磷酸化細(xì)胞核因子抗體
xy-6167R    NET1神經(jīng)上皮細(xì)胞轉(zhuǎn)化基因1抗體
xy-6181R    Nectin 3 細(xì)胞粘附分子3抗體（脊髓灰質(zhì)炎病毒受體相關(guān)蛋白3）
xy-11524R    NHLH2螺旋環(huán)螺旋蛋白2抗體
xy-12243R    Nodal胚胎發(fā)育相關(guān)蛋白Nodal抗體
xy-12272R    NA生殖細(xì)胞增殖相關(guān)蛋白NA抗體
xy-12273R    NOBOX同源盒蛋白NOBOX抗體
xy-12247R    NAC1轉(zhuǎn)錄因子NAC1抗體
xy-7122R    NGFR神經(jīng)生長因子受體抗體
xy-5517R    phospho-IKB epsilon (Ser157)磷酸化KB抑制蛋白激酶ε
xy-5519R    phospho-NRP1(Thr916)磷酸化神經(jīng)纖毛蛋白1抗體
xy-4140R    NF11型神經(jīng)纖維瘤抗體