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當(dāng)前位置:上海信裕生物科技有限公司>>抗體>>一抗>> 結(jié)締組織生長因子樣蛋白抗體
產(chǎn)品型號(hào)
品 牌Abcam
廠商性質(zhì)生產(chǎn)商
所 在 地上海
更新時(shí)間:2015-06-05 14:38:51瀏覽次數(shù):259次
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英文名稱 WISP2
中文名稱 結(jié)締組織生長因子樣蛋白抗體
別 名 CTGFL; CCN family member 5; CCN5; Connective tissue growth factor like protein; Connective tissue growth factor related protein 58; Connective tissue growth factor-like protein; Connective tissue growth factor-related protein 58; CT58; CTGF L; CTGFL; CTGF-L; WISP 2; WISP-2; Wisp2; WISP2_HUMAN; WNT1 inducible signaling pathway protein 2; WNT1-inducible-signaling pathway protein 2.
說 明 書 0.1ml 0.2ml
研究領(lǐng)域 腫瘤 細(xì)胞生物 免疫學(xué) 發(fā)育生物學(xué) 干細(xì)胞 生長因子和激素 轉(zhuǎn)錄調(diào)節(jié)因子
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep,
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
細(xì)胞定位 分泌型蛋白
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CTGFL
亞 型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
產(chǎn)品介紹 background:
WISP2 a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. WISP2 lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.
Function:
May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production.
Subcellular Location:
Secreted.
Tissue Specificity:
Expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart.xy-11146R PCDHGA3原鈣粘蛋白γA3抗體
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xy-0923R PDX1胰島素促進(jìn)因子抗體(胰十二指腸同源異型盒蛋白)
xy-0905R Acetyl-p53(K382)乙?;疨53(Lys382)抗體
xy-3737R Phospho-PPAR Gamma (ser112)磷酸化過氧化酶活化增生受體γ抗體
xy-3705R phospho-P53(Ser33)磷酸化腫瘤抑制基因P53抗體
xy-0198R PACAP receptor腺苷酸環(huán)化酶激活肽受體1抗體
xy-0318R PADI4關(guān)節(jié)炎相關(guān)基因抗體
xy-1119R PAF血小板活化因子抗體
xy-0828R Thrombin receptor蛋白酶激活受體-1抗體
xy-1178R PAR-2蛋白酶激活受體-2抗體
xy-1196R PAR4蛋白酶活化受體4抗體
xy-0769R PARP1多腺苷二磷酸多聚酶抗體/多聚ADP-核糖聚合酶1
xy-1097R PAX3配對盒基因3抗體
xy-1201R PAX8配對盒基因8抗體
xy-1102R PAX9配對盒基因9抗體
xy-1159R P-cadherinP-鈣粘附分子抗體
xy-0200R PACAP-38腺苷酸環(huán)化酶激活肽-38抗體
xy-0033R P53 protein(wt-p53)腫瘤抑制基因P53蛋白抗體(野生型P53)
xy-0723R P51A腫瘤抑制基因p63α抗體
xy-9719R PDE4A8磷酸二酯酶4A8抗體
xy-7559R PDGF AB+BB血小板源性生長因子AB+BB抗體
xy-2007R PCNA [Proliferation Marker]增殖細(xì)胞核抗原抗體
xy-11326R PCP4腦特異性多肽蛋白19抗體
xy-7690R P2RX4三磷酸腺苷門控陽離子通道蛋白抗體
xy-2978R Peroxiredoxin 2硫氧還蛋白過氧化物酶Ⅱ/巰基抗氧化蛋白抗體
xy-6878R p53 apoptosis effector related to PMP22p53凋亡相關(guān)作用蛋白PMP22抗體
xy-6369R PAICS磷酸核糖胺咪唑羧化酶抗體
xy-0161R p75 NGF Receptor神經(jīng)生長因子受體抗體
xy-8579R PMS1腫瘤錯(cuò)配修復(fù)基因PMS1抗體
xy-9446R AMPKγ2腺苷單磷酸活化蛋白激酶γ2抗體
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