轉(zhuǎn)錄因子7樣蛋白1抗體

英文名稱 TCF7L1
中文名稱 轉(zhuǎn)錄因子7樣蛋白1抗體
別    名 bHLHb21; HMG box transcription factor 3; HMG box transcription factor; OTTMUSP00000023419; T cell factor 3; TCF 3; TCF-3; TCF3; Tcf7l1; TF7L1_HUMAN; Transcription factor 7 like 1 (T-cell specific, HMG-box); Transcription factor 7 like 1; Transcription factor 7-like 1.

說 明 書 0.2ml  
研究領域 干細胞  轉(zhuǎn)錄調(diào)節(jié)因子  淋巴細胞  t-淋巴細胞  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Cow, Guinea Pig, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 63kDa
細胞定位 細胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TCF7L1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence. [provided by RefSeq, Nov 2010]

Function:
Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance.

Subcellular Location:
Nucleus.xy-11532R    PTPRN蛋白酪氨酸磷酸酶樣N前體蛋白抗體
xy-13775R    PSMD1226S蛋白酶調(diào)節(jié)亞型p55抗體
xy-13805R    PIPOX過氧化物酶肌氨酸氧化酶抗體
xy-2774R    prox1prox-1抗體
xy-2032R    PMP2周圍神經(jīng)髓鞘蛋白2抗體
xy-1493R    PKR蛋白激酶R抗體
xy-4125R    Pancreatic Lipase胰脂肪酶抗體
xy-4196R    Prostaglandin E Receptor EP2前列腺素E2受體2抗體
xy-4222R    PSME3蛋白酶體激活因子PA28γ抗體
xy-4197R    phospholamban受磷蛋白/心臟磷蛋白抗體
xy-7673R    PGRPS肽聚糖識別蛋白1抗體
xy-7674R    Porimin前細胞脹亡受體誘導膜損傷蛋白抗體
xy-7108R    PARP3多腺苷二磷酸多聚酶3抗體/多聚ADP-核糖聚合酶3
xy-7109R    PARP4多腺苷二磷酸多聚酶4抗體/多聚ADP-核糖聚合酶4
xy-13767R    PABPC4L聚腺苷酸養(yǎng)結(jié)合蛋白4抗體
xy-0644R    PTP4A2肝再生磷酸酯酶2抗體
xy-9513R    Protein Z蛋白Z抗體
xy-9512R    Protein S蛋白S抗體
xy-6984R    PEBP2B多瘤病毒增強了結(jié)合蛋白２β抗體
xy-1325R    PDE4D磷酸二酯酶4D抗體
xy-1875R    Profilin 2前纖維蛋白2抗體
xy-1873R    PRCP脯氨酰羧肽酶抗體
xy-1857R    P2Y4P2Y4受體抗體
xy-1869R    PEA3瘤促活化因子3抗體
xy-1436R    PBP磷脂酰乙醇胺結(jié)合蛋白1抗體
xy-1527R    peripherin外周蛋白抗體
xym-1625M    PSA(Pa3)人前列腺特異性抗原單克隆抗體(包被)
xym-1626M    PSA (PA5)鼠抗人前列腺特異性抗原單克隆抗體(檢測)
xy-1449R    Prohibitin抑制素/腫瘤抑制因子抗體
xy-1451R    PAFAH脂蛋白磷脂酶A2抗體
xy-0362R    Protein A重組金黃色葡萄球菌蛋白A抗體
xy-2395R    Pescadillo雌激素受體共調(diào)節(jié)因子抗體
xy-1518R    PersephinPSP抗體