TADA3L蛋白抗體

英文名稱 TADA3L
中文名稱 TADA3L蛋白抗體
別    名 ADA3; ADA3 homolog; ADA3-like protein; FLJ20221; FLJ21329; hADA3; Transcriptional adaptor 3 (NGG1 homolog yeast) like; Transcriptional adaptor 3 like.

說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Rabbit, Zebrafish, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 49kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TADA3L
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
DNA-binding transcriptional activator proteins increase the rate of transcription by interacting with the transcriptional machinery bound to the basal promoter in conjunction with adaptor proteins, possibly by acetylation and destabilization of nucleosomes. The protein encoded by this gene is a transcriptional activator adaptor and a component of the histone acetyl transferase (HAT) coactivator complex which plays a crucial role in chromatin modulation and cell cycle progression. Along with the other components of the complex, this protein links transcriptional activators bound to specific promoters, to histone acetylation and the transcriptional machinery. The protein is also involved in the stabilization and activation of the p53 tumor suppressor protein that plays a role in the cellular response to DNA damage. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013] 

Function:
Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53-dependent transcriptional activation. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.

Subunit:
The PCAF complex is composed of a number of TBP-associated factors (TAFS), such as TAF5, TAF5L, TAF6, TAF6L, TAF9, TAF10 and TAF12, PCAF, and also PCAF-associated factors (PAFs), such as TADA2L/ADA2, TADA3L/ADA3 and SPT3. Interacts directly with TADA2L and PCAF and also with the high-risk HPV oncoprotein E6. Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9. Component of the TFTC-HAT complex. Component of the ADA2A-containing complex (ATAC), composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1.

Tissue Specificity:
Ubiquitously expressed.xy-7933R    PPP2R3A蛋白質(zhì)磷酸酶2調(diào)節(jié)亞基3A抗體
xy-7929R    PPM1B蛋白質(zhì)磷酸酶1B抗體（PP2Cβ）
xy-7930R    PPM1G蛋白質(zhì)磷酸酶1G抗體（PP2Cγ）
xy-8633R    PFK16磷酸果糖激酶1抗體
xy-11686R    PROSAAS枯草溶菌素轉(zhuǎn)化酶1抑制劑抗體
xy-11687R    PROSAAS枯草溶菌素轉(zhuǎn)化酶1抑制劑抗體
xy-11991R    PPP2R5C蛋白質(zhì)磷酸酶2調(diào)節(jié)亞基5C/PP2A-B56-γ抗體
xy-11992R    PPP2R5D蛋白質(zhì)磷酸酶2調(diào)節(jié)亞基5D/PP2A-B56-δ抗體
xy-11994R    Phosphoserine/threonine磷酸化絲氨酸/蘇氨酸抗體
xy-11985R    PMCA3ATP酶鈣離子轉(zhuǎn)運蛋白PMCA3抗體
xy-11218R    Pumilio 1PUM1蛋白抗體
xy-11220R    PTBP1核糖核酸結(jié)合蛋白1抗體
xy-11215R    Plexin B2神經(jīng)叢蛋白B2抗體
xy-11222R    Phospho-p53BP1 (Ser1778)磷酸化p53結(jié)合蛋白1抗體
xy-11253R    PISTPDZ結(jié)構(gòu)域蛋白GOPC抗體
xy-11204R    PAX6轉(zhuǎn)錄因子Pax6抗體
xy-11206R    PLAGL1多型性腺瘤基因樣蛋白1抗體
xy-8687R    p53 (FL-393)腫瘤抑制基因p53抗體
xy-9511R    PAR4蛋白酶激活受體4抗體
xy-11139R    PCDHB5原鈣粘蛋白β5抗體
xy-6834R    PDCD7凋亡相關(guān)蛋白7抗體
xy-6768R    PEF1調(diào)亡誘導(dǎo)因子家族蛋白PEF1抗體
xy-6765R    Perilipin A+B脂滴包被蛋白A+B抗體
xy-6767R    PDC6I調(diào)亡誘導(dǎo)因子6相互作用蛋白/多巴胺受體相互作用蛋白4抗體
xym-4545M    Ractopamine (1B12)小鼠抗萊克多巴胺單克隆抗體
xy-9632R    PDZD9PDZ結(jié)構(gòu)域PDZK9蛋白抗體
xy-12106R    P2RX7嘌呤受體P2X7抗體
xy-12107R    P2RX1三磷酸腺苷受體受體P2X1抗體
xy-12108R    P2RX5三磷酸腺苷受體P2X5抗體
xy-12109R    P2X5b三磷酸腺苷受體P2X5b抗體