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目錄:愛必信(上海)生物科技有限公司>>細胞生物學>>重組蛋白>> abs04148CCL26 (24-94)

CCL26 (24-94)
  • CCL26 (24-94)
參考價 936
訂貨量 ≥1
具體成交價以合同協(xié)議為準
936
≥1
具體成交價以合同協(xié)議為準
  • 品牌 absin
  • 型號 abs04148
  • 廠商性質(zhì) 生產(chǎn)商
  • 所在地 上海市
屬性

供貨周期:一周 規(guī)格:10ug

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更新時間:2024-07-08 11:37:19瀏覽次數(shù):838評價

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供貨周期 一周 規(guī)格 10ug
愛必信特色產(chǎn)品線(全部現(xiàn)貨):
二抗、標簽抗體、對照抗體;WB相關(guān):ECL發(fā)光液、預(yù)染marker、預(yù)制膠;IHC相關(guān):二抗試劑盒、組化筆;IP/CoIP試劑盒;細胞因子、信號通路調(diào)節(jié)劑;血清、BSA、蛋白酶K、CTB、TTX、CEE;凋亡試劑盒、呼吸爆發(fā)試劑盒;動植物提取物...
概述
描述Recombinant Human C-C Motif Chemokine 26 is produced by our E.coli expression system and the target gene encoding Thr24-Leu94 is expressed.
別名C-C Motif Chemokine 26, CC Chemokine IMAC, Eotaxin-3, Macrophage Inflammatory Protein 4-Alpha, MIP-4-Alpha, Small-Inducible Cytokine A26, Thymic Stroma Chemokine-1, TSC-1, CCL26, SCYA26
形態(tài)Supplied as a 0.2 μm filtered solution of 20mM Tris, 1mM EDTA, 20% Glycerol, pH 9.0.
來源E.coli
氨基酸序列MTRGSDISKTCCFQYSHKPLPWTWVRSYEFTSNSCSQRAVIFTTKRGKKVCTHPRKKWVQKYISL LKTPKQL
內(nèi)毒素水平Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
Accession #Q9Y258
性能
背景Chemokine Ligand 26 protein (CCL26) is a novel small cytokine belonging to the CC chemokine family which is involved in immunoregulatory and inflammatory processes. CCL26 is constitutively expressed in thymus, but only transiently expressed in phytohemagglutinin-stimulated peripheral blood mononuclear cells. It specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. CCL26, along with Eotaxin-1 and Eotaxin-2, selectively activates the CC chemokine receptor 3 (CCR3). The Eotaxin-3-CCR3 interaction may play an important role in allergic diseases such as atopic dermatitis and bronchial asthma. The full-length cDNA for CCL26 encodes a protein of 94 amino acids with a putative signal peptide of either 23 or 26 amino acid residues. Both the 71 and 68 amino acid residue variants of recombinant CCL26 demonstrate equal potency in inducing chemotaxis of a human CCR3-transfected cell line. Unlike most other CC chemokines, CCL26 maps to human chromosome 7q11.2, within 40 kilobases of the Eotaxin-2 loci. CCL26 and Eotaxin-2 are unique in that they are the only chemokines identified to date that map to chromosome 7.
保存方法Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
純度Greater than 95% as determined by reducing SDS-PAGE.

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