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目錄:愛(ài)必信(上海)生物科技有限公司>>細(xì)胞生物學(xué)>>重組蛋白>> abs04170CXCL4/PF4 (C-6His)

CXCL4/PF4 (C-6His)
  • CXCL4/PF4 (C-6His)
參考價(jià) 840
訂貨量 ≥1
具體成交價(jià)以合同協(xié)議為準(zhǔn)
840
≥1
具體成交價(jià)以合同協(xié)議為準(zhǔn)
  • 品牌 absin
  • 型號(hào) abs04170
  • 廠(chǎng)商性質(zhì) 生產(chǎn)商
  • 所在地 上海市
屬性

供貨周期:一周 規(guī)格:10ug

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更新時(shí)間:2024-07-08 12:07:10瀏覽次數(shù):1062評(píng)價(jià)

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供貨周期 一周 規(guī)格 10ug
愛(ài)必信特色產(chǎn)品線(xiàn)(全部現(xiàn)貨):
二抗、標(biāo)簽抗體、對(duì)照抗體;WB相關(guān):ECL發(fā)光液、預(yù)染marker、預(yù)制膠;IHC相關(guān):二抗試劑盒、組化筆;IP/CoIP試劑盒;細(xì)胞因子、信號(hào)通路調(diào)節(jié)劑;血清、BSA、蛋白酶K、CTB、TTX、CEE;凋亡試劑盒、呼吸爆發(fā)試劑盒;動(dòng)植物提取物...
概述
描述Recombinant Human C-X-C Motif Chemokine 4 is produced by our Mammalian expression system and the target gene encoding Glu32-Ser101 is expressed with a 6His tag at the C-terminus.
別名Plaet Factor 4, PF-4, C-X-C Motif Chemokine 4, Iroplact, Oncostatin-A, PF4, CXCL4, SCYB4
形態(tài)Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
來(lái)源Human Cells
氨基酸序列EAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIK KLLESHHHHHH
內(nèi)毒素水平Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
Accession #P02776
性能
背景Human Chemokine (C-X-C motif) Ligand 4 (CXCL4) is expressed in megakaryocytes and stored in the alpha-granules of plaets. CXCL4 contains several heparin-binding sites at the C-terminal region and binds heparin with high affinity. The active CXCL4 protein is a tetramer. Human and mouse CXCL4 share 64% sequence identity. CXCL4 is chemotactic for neutrophils, fibroblasts and monocytes and plays a critical role in inflammation and wound repair. CXCL4 functions via a splice variant of the chemokine receptor CXCR3, known as CXCR3B. The major physiologic role of CXCL4 appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. In contrast to other CXC chemokines, CXCL4 lacks chemotactic activity for polymorphonuclear granulocytes.
溶解方法Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
保存方法Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
純度Greater than 95% as determined by reducing SDS-PAGE. 

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