496849-46-8，分子式：C67H85N15O11螯合劑

英文名：Tyr-(D-Dab4,Arg5,D-Trp8)-cyclo-Somatostatin-14 (4-11) trifluoroacetate salt

H-TYR-CYCLO(-D-DAB-ARG-PHE-PHE-D-TRP-LYS-THR-PHE)

TYR-(D-DAB4,ARG5,D-TRP8)-CYCLO-SOMATOSTATIN-14 (4-11)

H-Tyr-cyclo(-D-Dab-Arg-Phe-Phe-D-Trp-Lys-Thr-Phe)

CAS號：496849-46-8

分子式：C67H85N15O11

分子量：1276.49

結(jié)構(gòu)式：

五種生長抑素受體的高親和力配體（sst1-sst5）。在主要表達sst2和sst5受體的AtT-20小鼠垂體前葉腫瘤細胞中，發(fā)現(xiàn)這種生長抑素類似物的結(jié)合親和力高于生長抑素14和奧曲肽。然而，在癲癇發(fā)生模型中，KE 108沒有表現(xiàn)出抗癲癇活性，這表明合成配體對所有已知生長抑素受體的高效力和有效性可能不會*重現(xiàn)天然配體的作用。

相關化合物:

(D-Trp8)-Somatostatin-14 trifluoroacetate salt

58976-46-8

(D-Phe5,Cys6.11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide

340821-13-8

(D-2-Nal5,Cys6.11,Tyr7,D-Trp8,Val10,2-Nal12)-Somatostatin-14 (5-12) amide trifluoroacetate salt

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H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 trifluoroacetate salt (Disulfide bond)

103429-31-8

(Des-Ala1,des-Gly2,His4·5,D-Trp8)-Somatostatin-14

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Tyr-Somatostatin-14

58100-03-1

(Des-Gly10,D-Tyr5,D-His(Bzl)6,Pro-NHEt9)-LHRH trifluoroacetate salt

321709-40-4

(D-Arg2)-Dermorphin (1-4) amide trifluoroacetate salt

100304-60-7

(D-His(Bzl)6,Pro-NHEt9)-LHRH (4-9) trifluoroacetate salt

134009-09-9

496849-46-8，分子式：C67H85N15O11螯合劑