百日咳IgG抗體定量酶聯(lián)免疫法檢測試劑盒

英文名稱：Bordela Pertussis IgG (quant.)

廣州健侖生物科技有限公司

（廣州健侖生物科技有限公司是集研制開發(fā)、銷售、服務(wù)于一體的優(yōu)良企業(yè),公司產(chǎn)品涉及臨床快速診斷試劑、食品安全檢測試劑，違禁品快速檢測，動(dòng)物疾病防疫檢測試劑，免疫診斷試劑、臨床血液學(xué)和體液學(xué)檢驗(yàn)試劑、微生物檢驗(yàn)試劑、分子生物學(xué)檢驗(yàn)試劑、臨床生化試劑、有機(jī)試劑等眾多領(lǐng)域，同時(shí)核心代理Panbio、FOCUS、Qiagen、IBL、CORTEZ、Fuller、Inbios、BinaxNOW、LumuQuick、日本富士、日本生研等多家有名診斷產(chǎn)品集團(tuán)公司產(chǎn)品，致力于為商檢單位、疾病預(yù)防控制中心、海關(guān)出入境檢疫局、衛(wèi)生防疫單位,緝毒系統(tǒng)，戒毒中心，檢驗(yàn)檢疫單位、生化企業(yè)、科研院所、醫(yī)療機(jī)構(gòu)等機(jī)構(gòu)與行業(yè)提供*、高品質(zhì)的產(chǎn)品服務(wù)。此外，本公司還開展食品、衛(wèi)生、環(huán)境、藥品等多方面的第三方檢測服務(wù)。）

主要用途：用于定量測定人血清、腦脊液或血漿中的百日咳抗體。

產(chǎn)品規(guī)格：96T/盒

存儲(chǔ)條件：4-8℃

保質(zhì)期：18個(gè)月

【產(chǎn)品介紹】

Pertussis IgG Antibody Quantification Kit (Enzyme-Linked Immunosorbent Assay) For the quantitative detection of anti-pertussis antibodies in human serum and plasma. The reagent can be used for the diagnosis and epidemiological study of acute or recent pertussis infection, while IgG-ELISA reagent is used to monitor the vaccination.

Bordela pertussis belongs to the genus Bordela and is a small globular Gram-negative bacillus. Bordela pertussis is the causative agent of pertussis, a global infectious disease that spreads from person to person through droplets. Babies 0-4 years old are particularly vulnerable to infection. Infants and toddlers have a very high mortality rate High (Infant mortality rate within 1 year old is 60%) 1.

Bordela pertussis is attached to the mucosal ciliated cells of the respiratory tract through its surface ligands. One of the important adhesion proteins is also an important immunogen (antigen), known as Filamentous HemAgglutinin (hereinafter referred to as "FHA"). The synergistic effect of several virulence factors will promote the colonization of bacteria in the respiratory tract and trigger infection.

Bordela pertussis synthesizes and secretes a specific toxin known as Pertussis Toxin (PT), an important virulence factor. Pertussis toxin can produce complex biological effects, such as leukocytosis, lymphocytosis and the body's sensitivity to histamine increased.

A typical pertussis in three stages, after 1-2 weeks of incubation, enters the period of mucosal inflammation (highly contagious), which lasts 1-2 weeks, with a noncharacteristic cough , Rhinitis, and conjunctivitis; the next is the spasm (paroxysmal cough), paroxysmal cough often accompanied by vomiting mucus, laryngospasm and bronchospasm, resulting in infantile bruising, then repeated, sharp Of breath, then continue to cough, severe cases of seizures up to 50 times a day; 4-6 weeks later, the frequency of disease attacks will be reduced and gradually calm down (remission, the duration of up to 6 months).

Infected patients usually produce IgM-, IgA- and IgG-antibodies at the second week of the spasticity (see Figure 1), IgM-antibodies last 2-3 months, and IgA-antibodies rise from the spasm Start for 4-6 months.

IgG-antibodies peak at 6-8 weeks and are detectable until adulthood; IgM- and IgG-antibodies are produced immediay after vaccination; for infants and young children up to 6 months, specific IgM- Antibodies are suitable for the early diagnosis of recent infections, whereas specific IgA-antibodies show better diagnostic properties in infants and young children over 6 months; infants within 3 months do not produce IgA-antibodies.

【檢測原理】

用抗原包被微量板孔，制成固相載體。加患者血清到板孔中，其所含的抗體特異性地與固相載體中現(xiàn)存抗原結(jié)合，形成免疫復(fù)合物。除去多余物質(zhì)后，加入結(jié)合了堿性磷酸酶的IgG、IgA或IgM抗體，使之與上述免疫復(fù)合物反應(yīng)。洗板，除去多余的結(jié)合物，加入底物（對硝基苯磷酸鹽）。其與酶結(jié)合的免疫復(fù)合物反應(yīng)，產(chǎn)生有顏色產(chǎn)物，顏色強(qiáng)度與特異性抗體含量成正比。

百日咳IgG抗體定量酶聯(lián)免疫法檢測試劑盒

【試劑盒的組成】

ELISA classic百日咳 IgG: 

我司同時(shí)還提供、美國FOCUS、西班牙DIA、美國trinity等試劑盒：

麻疹、風(fēng)疹、甲流 、乙流、單皰疹1型、單皰疹2型、百日咳、百日咳毒素、腮腺炎、帶狀皰疹、單純皰疹、HSV1型特異性、巨細(xì)胞-特異、風(fēng)疹-特異、弓形蟲-特異、棘球?qū)佟⑹确诬妶F(tuán)菌、破傷風(fēng)、蜱傳腦炎、幽門螺旋桿菌、白色念珠菌、博氏疏螺旋體、細(xì)小病毒、鉤端螺旋體、腺病毒、Q熱柯克斯體、煙曲霉菌、?？刹《?/span>、EB病毒、衣原體、耶爾森菌、空腸彎曲桿菌、炭疽桿菌、白喉、腸道病毒、柯薩奇病毒、肺炎衣原體、沙眼衣原體、土拉弗朗西斯菌、漢坦病毒、類風(fēng)濕因子、呼吸道合胞病毒、單純皰疹病毒質(zhì)控品、巨細(xì)胞質(zhì)控品、弓形蟲質(zhì)控品、風(fēng)疹麻疹質(zhì)控品等試劑盒以。

歡迎咨詢

歡迎咨詢   

二維碼掃一掃

【公司名稱】 廣州健侖生物科技有限公司
【市場部】
【】
【電子郵件】 Service@jianlun.com  Jim@jianlun.com
【騰訊 】
【公司】 www.jianlun。。ｃｏｍ
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號(hào)二期2幢一層101-3室